Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| M0QZW2 | CD70 | CD70 molecule | Homo sapiens (Human) | 65 aa |
Protein Details: M0QZW2 (CD70)
Protein Information
| Accession | M0QZW2 |
|---|---|
| Protein Names | CD70 molecule |
| Gene Symbol | CD70 |
| Organism | Homo sapiens (Human) |
| Length | 65 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPEEGSGCSV11RRRPYGCVLR21AALVPLVAGL31VICLVVCIQR41FAQAQQQLPL
51-6551ESLGWDVAEL61QLNHT
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 8 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.91
Deep-Palm: 0.06
|
| 17 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.81
Deep-Palm: 0.98
|
| 33 | CD70 antigen | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.98
|
|
| 37 | CD70 antigen | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
PC3
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 97 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 144 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 157 | R → C | 0.006993 | SNP | Missense Mutation | LAML |
| 192 | R → C | 0.005013 | SNP | Missense Mutation | COAD |