Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| M0R116 | ATP1A3 | Sodium/potassium-transporting ATPase subunit alpha | Homo sapiens (Human) | 983 aa |
Protein Details: M0R116 (ATP1A3)
Protein Information
| Accession | M0R116 |
|---|---|
| Protein Names | Sodium/potassium-transporting ATPase subunit alpha |
| Gene Symbol | ATP1A3 |
| Organism | Homo sapiens (Human) |
| Length | 983 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 29575903 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
4
Cerebral cortex
Specificity: 0.667
4/4 (100.0%)
1
HeLa cells
Specificity: 0.167
1/1 (100.0%)
1
Prefrontal cortex
Specificity: 0.167
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MTEHKMSVEE11VCRKYNTDCV21QGLTHSKAQE31ILARDGPNAL41TPPPTTPEWV
51-10051KFCRQLFGGF61SILLWIGAIL71CFLAYGIQAG81TEDDPSGDNL91YLGIVLAAVV
101-150101IITGCFSYYQ111EAKSSKIMES121FKNMVPQQAL131VIREGEKMQV141NAEEVVVGDL
151-200151VEIKGGDRVP161ADLRIISAHG171CKVDNSSLTG181ESEPQTRSPD191CTHDNPLETR
201-250201NITFFSTNCV211EGTARGVVVA221TGDRTVMGRI231ATLASGLEVG241KTPIAIEIEH
251-300251FIQLITGVAV261FLGVSFFILS271LILGYTWLEA281VIFLIGIIVA291NVPEGLLATV
301-350301TVCLTLTAKR311MARKNCLVKN321LEAVETLGST331STICSDKTGT341LTQNRMTVAH
351-400351MWFDNQIHEA361DTTEDQSGTS371FDKSSHTWVA381LSHIAGLCNR391AVFKGGQDNI
401-450401PVLKRDVAGD411ASESALLKCI421ELSSGSVKLM431RERNKKVAEI441PFNSTNKYQL
451-500451SIHETEDPND461NRYLLVMKGA471PERILDRCST481ILLQGKEQPL491DEEMKEAFQN
501-550501AYLELGGLGE511RVLGFCHYYL521PEEQFPKGFA531FDCDDVNFTT541DNLCFVGLMS
551-600551MIDPPRAAVP561DAVGKCRSAG571IKVIMVTGDH581PITAKAIAKG591VGIISEGNET
601-650601VEDIAARLNI611PVSQVNPRDA621KACVIHGTDL631KDFTSEQIDE641ILQNHTEIVF
651-700651ARTSPQQKLI661IVEGCQRQGA671IVAVTGDGVN681DSPALKKADI691GVAMGIAGSD
701-750701VSKQAADMIL711LDDNFASIVT721GVEEGRLIFD731NLKKSIAYTL741TSNIPEITPF
751-800751LLFIMANIPL761PLGTITILCI771DLGTDMVPAI781SLAYEAAESD791IMKRQPRNPR
801-850801TDKLVNERLI811SMAYGQIGMI821QALGGFFSYF831VILAENGFLP841GNLVGIRLNW
851-900851DDRTVNDLED861SYGQQWTYEQ871RKVVEFTCHT881AFFVSIVVVQ891WADLIICKTR
901-950901RNSVFQQGMK911NKILIFGLFE921ETALAAFLSY931CPGMDVALRM941YPLKPSWWFC
951-983951AFPYSFLIFV961YDEIRKLILR971RNPGGWVEKE981TYY
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 53 | Prediction (Low) | - | - |
| 105 | Prediction (Medium) | - | - |
| 171 | Prediction (Low) | - | - |
| 303 | Prediction (Medium) | - | - |
| 316 | Prediction (High) | - | - |
| 334 | Prediction (Low) | - | - |
| 388 | Prediction (Medium) | - | - |
| 478 | Prediction (Medium) | - | - |
| 516 | Prediction (Low) | - | - |
| 566 | Prediction (Medium) | - | - |
| 623 | Prediction (Low) | - | - |
| 665 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
| 897 | Prediction (High) | - | - |
| 931 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 19 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 19 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 185 | G → C | 0.004219 | SNP | Missense Mutation | SARC |
| 217 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 259 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 340 | R → C | 0.002545 | SNP | Missense Mutation | GBM |
| 346 | C → C | 0.001887 | SNP | Silent | UCEC |
| 346 | C → S | 0.006993 | SNP | Missense Mutation | LAML |
| 375 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 420 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 420 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 461 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 463 | R → C | 0.027027 | SNP | Missense Mutation | DLBC |
| 478 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 541 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 546 | C → S | 0.002545 | SNP | Missense Mutation | GBM |
| 682 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 756 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 793 | G → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 803 | G → C | 0.005435 | SNP | Missense Mutation | ESCA |
| 980 | C → Vfs*136 | 0.002294 | DEL | Frame Shift Del | OV |
| 995 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 995 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 1000 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |