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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
M0R2D3 TUBB4A Tubulin beta 4A class IVa Homo sapiens (Human) 340 aa

Protein Details: M0R2D3 (TUBB4A)

Protein Information
Accession M0R2D3
Protein Names Tubulin beta 4A class IVa
Gene Symbol TUBB4A
Organism Homo sapiens (Human)
Length 340 aa
Isoforms No isoforms
Related PMIDs 31251020
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 1.000
35/46 (76.1%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MREIVHLQAG11QCGNQIGAKF21WEVISDEHGI31DPTGTYHGDS41DLQLERINVY
51-10051YNEEFPDRIM61NTFSVVPSPK71VSDTVVEPYN81ATLSVHQLVE91NTDETYCIDN
101-150101EALYDICFRT111LKLTTPTYGD121LNHLVSATMS131GVTTCLRFPG141QLNADLRKLA
151-200151VNMVPFPRLH161FFMPGFAPLT171SRGSQQYRAL181TVPELTQQMF191DAKNMMAACD
201-250201PRHGRYLTVA211AVFRGRMSMK221EVDEQMLSVQ231SKNSSYFVEW241IPNNVKTAVC
251-300251DIPPRGLKMA261ATFIGNSTAI271QELFKRISEQ281FTAMFRRKAF291LHWYTGEGMD
301-340301EMEFTEAESN311MNDLVSEYQQ321YQDATAEEGE331FEEEAEEEVA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
12 Prediction (Low) - -
107 Prediction (Medium) - -
135 CYSMODDB SWISSPALM DBPTM Prediction (High) - -
199 Prediction (High) - -
250 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
77 R → C 0.002141 SNP Missense Mutation SKCM
127 C → C 0.001887 SNP Silent UCEC
156 R → C 0.002020 SNP Missense Mutation PRAD
162 R → C 0.002506 SNP Missense Mutation COAD
183 Y → C 0.002033 SNP Missense Mutation LUSC
213 R → C 0.001969 SNP Missense Mutation HNSC
251 R → C 0.002506 SNP Missense Mutation COAD
251 R → C 0.001969 SNP Missense Mutation LGG
262 R → C 0.002288 SNP Missense Mutation STAD
303 C → C 0.002545 SNP Silent GBM
309 R → C 0.002545 SNP Missense Mutation GBM
309 R → C 0.001887 SNP Missense Mutation UCEC
354 C → C 0.002506 SNP Silent COAD
354 C → C 0.003774 SNP Silent UCEC
380 R → C 0.001887 SNP Missense Mutation UCEC
391 R → C 0.002020 SNP Missense Mutation PRAD
391 R → C 0.002294 SNP Missense Mutation OV