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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O00116 AGPS; AAG5 Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) … Homo sapiens (Human) 658 aa

Protein Details: O00116 (AGPS)

Protein Information
Accession O00116
Protein Names Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Aging-associated gene 5 protein) (Alkylglycerone-phosphate synthase)
Gene Symbol AGPS; AAG5
Organism Homo sapiens (Human)
Length 658 aa
Isoforms No isoforms
Related PMIDs 29733200 31251020 31382980 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.703
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
26
LNCaP cells
Specificity: 0.703
26/46 (56.5%)
4
HAP1 cells
Specificity: 0.108
4/10 (40.0%)
4
293T cells
Specificity: 0.108
4/10 (40.0%)
2
PC3 cells
Specificity: 0.054
2/4 (50.0%)
1
U937 cells
Specificity: 0.027
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAEAAAAAGG11TGLGAGASYG21SAADRDRDPD31PDRAGRRLRV41LSGHLLGRPR
51-10051EALSTNECKA61RRAASAATAA71PTATPAAQES81GTIPKKRQEV91MKWNGWGYND
101-150101SKFIFNKKGQ111IELTGKRYPL121SGMGLPTFKE131WIQNTLGVNV141EHKTTSKASL
151-200151NPSDTPPSVV161NEDFLHDLKE171TNISYSQEAD181DRVFRAHGHC191LHEIFLLREG
201-250201MFERIPDIVL211WPTCHDDVVK221IVNLACKYNL231CIIPIGGGTS241VSYGLMCPAD
251-300251ETRTIISLDT261SQMNRILWVD271ENNLTAHVEA281GITGQELERQ291LKESGYCTGH
301-350301EPDSLEFSTV311GGWVSTRASG321MKKNIYGNIE331DLVVHIKMVT341PRGIIEKSCQ
351-400351GPRMSTGPDI361HHFIMGSEGT371LGVITEATIK381IRPVPEYQKY391GSVAFPNFEQ
401-450401GVACLREIAK411QRCAPASIRL421MDNKQFQFGH431ALKPQVSSIF441TSFLDGLKKF
451-500451YITKFKGFDP461NQLSVATLLF471EGDREKVLQH481EKQVYDIAAK491FGGLAAGEDN
501-550501GQRGYLLTYV511IAYIRDLALE521YYVLGESFET531SAPWDRVVDL541CRNVKERITR
551-600551ECKEKGVQFA561PFSTCRVTQT571YDAGACIYFY581FAFNYRGISD591PLTVFEQTEA
601-650601AAREEILANG611GSLSHHHGVG621KLRKQWLKES631ISDVGFGMLK641SVKEYVDPNN
651-658651IFGNRNLL
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
58 Prediction (Medium) - -
190 Prediction (Low) - -
226 Prediction (Medium) - -
231 Prediction (Medium) - -
349 Prediction (Low) - -
404 Prediction (Medium) - -
413 Prediction (Medium) - -
565 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
58 C → Y 0.001887 SNP Missense Mutation UCEC
317 R → C 0.005435 SNP Missense Mutation ESCA
474 R → C 0.002141 SNP Missense Mutation SKCM
474 R → C 0.001887 SNP Missense Mutation UCEC
491 F → C 0.001887 SNP Missense Mutation UCEC
565 C → C 0.001764 SNP Splice Region LUAD
608 A → Cfs*2 0.001887 INS Frame Shift Ins UCEC
632 S → C 0.002427 SNP Missense Mutation BLCA