Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O00400 | SLC33A1 | Acetyl-coenzyme A transporter 1 (AT-1) … | Homo sapiens (Human) | 549 aa |
Protein Details: O00400 (SLC33A1)
Protein Information
| Accession | O00400 |
|---|---|
| Protein Names | Acetyl-coenzyme A transporter 1 (AT-1) (Acetyl-CoA transporter 1) (Solute carrier family 33 member 1) |
| Gene Symbol | SLC33A1 |
| Organism | Homo sapiens (Human) |
| Length | 549 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSPTISHKDS11SRQRRPGNFS21HSLDMKSGPL31PPGGWDDSHL41DSAGREGDRE
51-10051ALLGDTGTGD61FLKAPQSFRA71ELSSILLLLF81LYVLQGIPLG91LAGSIPLILQ
101-150101SKNVSYTDQA111FFSFVFWPFS121LKLLWAPLVD131AVYVKNFGRR141KSWLVPTQYI
151-200151LGLFMIYLST161QVDRLLGNTD171DRTPDVIALT181VAFFLFEFLA191ATQDIAVDGW
201-250201ALTMLSRENV211GYASTCNSVG221QTAGYFLGNV231LFLALESADF241CNKYLRFQPQ
251-300251PRGIVTLSDF261LFFWGTVFLI271TTTLVALLKK281ENEVSVVKEE291TQGITDTYKL
301-350301LFAIIKMPAV311LTFCLLILTA321KIGFSAADAV331TGLKLVEEGV341PKEHLALLAV
351-400351PMVPLQIILP361LIISKYTAGP371QPLNTFYKAM381PYRLLLGLEY391ALLVWWTPKV
401-450401EHQGGFPIYY411YIVVLLSYAL421HQVTVYSMYV431SIMAFNAKVS441DPLIGGTYMT
451-500451LLNTVSNLGG461NWPSTVALWL471VDPLTVKECV481GASNQNCRTP491DAVELCKKLG
501-549501GSCVTALDGY511YVESIICVFI521GFGWWFFLGP531KFKKLQDEGS541SSWKCKRNN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 216 | - | - | - |
Deep-Palm: 0.74
|
|
| 241 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.79
|
|
| 314 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.91
|
|
| 479 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.94
|
|
| 487 | - | - | - |
Deep-Palm: 0.93
|
|
| 496 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.94
|
| 503 | - | - | - |
Deep-Palm: 0.96
|
|
| 517 | - | - | - |
Deep-Palm: 0.07
|
|
| 545 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 411 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 479 | C → S | 0.002141 | SNP | Missense Mutation | SKCM |
| 479 | C → F | 0.002976 | SNP | Missense Mutation | KIRC |
| 501 | G → _C503del | 0.002033 | DEL | In Frame Del | LUSC |
| 514 | S → C | 0.001969 | SNP | Missense Mutation | LGG |
| 522 | F → C | 0.002506 | SNP | Missense Mutation | COAD |