Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O00400 | SLC33A1; ACATN; AT1 | Acetyl-coenzyme A transporter 1 (AT-1) … | Homo sapiens (Human) | 549 aa |
Protein Details: O00400 (SLC33A1)
Protein Information
| Accession | O00400 |
|---|---|
| Protein Names | Acetyl-coenzyme A transporter 1 (AT-1) (Acetyl-CoA transporter 1) (Solute carrier family 33 member 1) |
| Gene Symbol | SLC33A1; ACATN; AT1 |
| Organism | Homo sapiens (Human) |
| Length | 549 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.842
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
16
LNCaP cells
Specificity: 0.842
16/46 (34.8%)
3
PC3 cells
Specificity: 0.158
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSPTISHKDS11SRQRRPGNFS21HSLDMKSGPL31PPGGWDDSHL41DSAGREGDRE
51-10051ALLGDTGTGD61FLKAPQSFRA71ELSSILLLLF81LYVLQGIPLG91LAGSIPLILQ
101-150101SKNVSYTDQA111FFSFVFWPFS121LKLLWAPLVD131AVYVKNFGRR141KSWLVPTQYI
151-200151LGLFMIYLST161QVDRLLGNTD171DRTPDVIALT181VAFFLFEFLA191ATQDIAVDGW
201-250201ALTMLSRENV211GYASTCNSVG221QTAGYFLGNV231LFLALESADF241CNKYLRFQPQ
251-300251PRGIVTLSDF261LFFWGTVFLI271TTTLVALLKK281ENEVSVVKEE291TQGITDTYKL
301-350301LFAIIKMPAV311LTFCLLILTA321KIGFSAADAV331TGLKLVEEGV341PKEHLALLAV
351-400351PMVPLQIILP361LIISKYTAGP371QPLNTFYKAM381PYRLLLGLEY391ALLVWWTPKV
401-450401EHQGGFPIYY411YIVVLLSYAL421HQVTVYSMYV431SIMAFNAKVS441DPLIGGTYMT
451-500451LLNTVSNLGG461NWPSTVALWL471VDPLTVKECV481GASNQNCRTP491DAVELCKKLG
501-549501GSCVTALDGY511YVESIICVFI521GFGWWFFLGP531KFKKLQDEGS541SSWKCKRNN
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 241 | Prediction (Medium) | - | - |
| 314 | Prediction (Medium) | - | - |
| 479 | Prediction (Medium) | - | - |
| 496 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | - |
| 545 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 411 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 479 | C → S | 0.002141 | SNP | Missense Mutation | SKCM |
| 479 | C → F | 0.002976 | SNP | Missense Mutation | KIRC |
| 501 | G → _C503del | 0.002033 | DEL | In Frame Del | LUSC |
| 514 | S → C | 0.001969 | SNP | Missense Mutation | LGG |
| 522 | F → C | 0.002506 | SNP | Missense Mutation | COAD |