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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O00501 CLDN5; AWAL; TMVCF Claudin-5 (Transmembrane protein deleted in … Homo sapiens (Human) 218 aa

Protein Details: O00501 (CLDN5)

Protein Information
Accession O00501
Protein Names Claudin-5 (Transmembrane protein deleted in VCFS) (TMDVCF)
Gene Symbol CLDN5; AWAL; TMVCF
Organism Homo sapiens (Human)
Length 218 aa
Isoforms No isoforms
Related PMIDs 24357059
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
1
Endothelial cells
Specificity: 1.000
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGSAALEILG11LVLCLVGWGG21LILACGLPMW31QVTAFLDHNI41VTAQTTWKGL
51-10051WMSCVVQSTG61HMQCKVYDSV71LALSTEVQAA81RALTVSAVLL91AFVALFVTLA
101-150101GAQCTTCVAP111GPAKARVALT121GGVLYLFCGL131LALVPLCWFA141NIVVREFYDP
151-200151SVPVSQKYEL161GAALYIGWAA171TALLMVGGCL181LCCGAWVCTG191RPDLSFPVKY
201-218201SAPRRPTATG211DYDKKNYV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
25 Prediction (Low) - -
104 Prediction (Low) - -
107 Prediction (Medium) - -
137 Prediction (Medium) - -
179 Prediction (Low) - -
182 Prediction (Medium) - -
183 Prediction (Medium) - -
188 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
47 W → C 0.010870 SNP Missense Mutation ACC
54 C → R 0.001014 SNP Missense Mutation BRCA
107 C → Sfs*70 0.002747 DEL Frame Shift Del LIHC
107 C → Y 0.002747 SNP Missense Mutation LIHC