Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O08529 | Capn2 | Calpain-2 catalytic subunit (EC 3.4.22.53) … | Mus musculus (Mouse) | 700 aa |
Protein Details: O08529 (Capn2)
Protein Information
| Accession | O08529 |
|---|---|
| Protein Names | Calpain-2 catalytic subunit (EC 3.4.22.53) (80 kDa M-calpain subunit) (CALP80) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain) |
| Gene Symbol | Capn2 |
| Organism | Mus musculus (Mouse) |
| Length | 700 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 34200797 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAGIAIKLAK11DREAAEGLGS21HERAIKYLNQ31DYETLRNECL41EAGALFQDPS
51-10051FPALPSSLGY61KELGPYSSKT71RGIEWKRPTE81ICADPQFIIG91GATRTDICQG
101-150101ALGDCWLLAA111IASLTLNEEI121LARVVPPDQS131FQENYAGIFH141FQFWQYGEWV
151-200151EVVVDDRLPT161KDGELLFVHS171AEGSEFWSAL181LEKAYAKING191CYEALSGGAT
201-250201TEGFEDFTGG211IAEWYELRKP221PPNLFKIIQK231ALEKGSLLGC241SIDITSAADS
251-300251EAVTYQKLVK261GHAYSVTGAE271EVESSGSLQK281LIRIRNPWGQ291VEWTGKWNDN
301-350301CPSWNTVDPE311VRANLTERQE321DGEFWMSFSD331FLRHYSRLEI341CNLTPDTLTC
351-400351DSYKKWKLTK361MDGNWRRGST371AGGCRNYPNT381FWMNPQYLIK391LEEEDEDEED
401-450401GERGCTFLVG411LIQKHRRRQR421KMGEDMHTIG431FGIYEVPEEL441TGQTNIHLGK
451-500451NFFLTTRARE461RSDTFINLRE471VLNRFKLPPG481EYVLVPSTFE491PHKDGDFCIR
501-550501VFSEKKADYQ511AVDDEIEANI521EEIDANEEDI531DDGFRRLFVQ541LAGEDAEISA
551-600551FELQTILRRV561LAKRQDIKSD571GFSIETCKIM581VDMLDEDGSG591KLGLKEFYIL
601-650601WTKIQKYQKI611YREIDVDRSG621TMNSYEMRKA631LEEAGFKLPC641QLHQVIVARF
651-700651ADDELIIDFD661NFVRCLVRLE671TLFKIFKQLD681PENTGTIQLN691LASWLSFSVL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 39 | Papain-like cysteine peptidase superfamily | - | - |
Deep-Palm: 0.91
|
|
| 82 | - | - | - |
Deep-Palm: 0.83
|
|
| 98 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.63
|
|
| 105 | - | - | - |
Deep-Palm: 0.83
|
|
| 191 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.94
|
|
| 240 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.98
|
|
| 301 | - | - | - |
Deep-Palm: 0.29
|
|
| 341 | Calpain family cysteine protease |
Brain
(34200797)
| - |
GPS-Palm: 0.67
Deep-Palm: 0.43
|
|
| 350 | - |
Brain
(34200797)
| - |
GPS-Palm: 0.84
Deep-Palm: 0.32
|
|
| 374 | - | - | - |
Deep-Palm: 0.08
|
|
| 405 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.96
|
|
| 498 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.46
|
|
| 577 | - | - | - |
Deep-Palm: 0.63
|
|
| 640 | SWISSPALM DBPTM CYSMODDB | - |
liver
(26165157)
|
Brain
(35358180)
|
GPS-Palm: 0.94
Deep-Palm: 0.97
|
| 665 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.89
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
4
Brain
Specificity: 0.167
4/4 (100.0%)
3
Liver
Specificity: 0.125
3/3 (100.0%)
2
Testis
Specificity: 0.083
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
15
Brain tissue (Mass)
Specificity: 0.625
15/56 (26.8%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.