Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O08530 S1pr1 Sphingosine 1-phosphate receptor 1 (S1P … Mus musculus (Mouse) 382 aa

Protein Details: O08530 (S1pr1)

Protein Information
AccessionO08530
Protein NamesSphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Lysophospholipid receptor B1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363)
Gene SymbolS1pr1
OrganismMus musculus (Mouse)
Length382 aa
IsoformsNo isoforms
Related PMIDs 29733200 34200797 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVSTSIPEVK11ALRSSVSDYG21NYDIIVRHYN31YTGKLNIGAE41KDHGIKLTSV
51-10051VFILICCFII61LENIFVLLTI71WKTKKFHRPM81YYFIGNLALS91DLLAGVAYTA
101-150101NLLLSGATTY111KLTPAQWFLR121EGSMFVALSA131SVFSLLAIAI141ERYITMLKMK
151-200151LHNGSNSSRS161FLLISACWVI171SLILGGLPIM181GWNCISSLSS191CSTVLPLYHK
201-250201HYILFCTTVF211TLLLLSIVIL221YCRIYSLVRT231RSRRLTFRKN241ISKASRSSEK
251-300251SLALLKTVII261VLSVFIACWA271PLFILLLLDV281GCKAKTCDIL291YKAEYFLVLA
301-350301VLNSGTNPII311YTLTNKEMRR321AFIRIVSCCK331CPNGDSAGKF341KRPIIPGMEF
351-382351SRSKSDNSSH361PQKDDGDNPE371TIMSSGNVNS381SS
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
56 - - -
GPS-Palm: 0.74
Deep-Palm: 0.15
57 - - -
Deep-Palm: 0.11
167 - - -
Deep-Palm: 0.88
184 - - -
GPS-Palm: 0.69
Deep-Palm: 0.90
191 - - -
GPS-Palm: 0.69
Deep-Palm: 0.19
206 - - -
GPS-Palm: 0.66
Deep-Palm: 0.37
222 - - -
GPS-Palm: 0.94
Deep-Palm: 0.96
268 - - -
Deep-Palm: 0.70
282 - - -
GPS-Palm: 0.86
Deep-Palm: 0.96
287 - -
Brain (35358180)
GPS-Palm: 0.70
Deep-Palm: 0.97
328 SWISSPALM DBPTM CYSMODDB -
Brain (34200797)
Forebrain (28680068)
-
GPS-Palm: 0.91
Deep-Palm: 0.68
329 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
-
GPS-Palm: 0.89
Deep-Palm: 0.64
331 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
-
GPS-Palm: 0.74
Deep-Palm: 0.58
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
Brain
Specificity: 0.267
4/4 (100.0%)
2
Liver
Specificity: 0.133
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
9
Brain tissue (Mass)
Specificity: 0.600
9/56 (16.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine