Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O08688 Capn5 Calpain-5 (EC 3.4.22.-) (New calpain … Mus musculus (Mouse) 640 aa

Protein Details: O08688 (Capn5)

Protein Information
AccessionO08688
Protein NamesCalpain-5 (EC 3.4.22.-) (New calpain 3) (nCL-3)
Gene SymbolCapn5
OrganismMus musculus (Mouse)
Length640 aa
IsoformsNo isoforms
Related PMIDs 29733200 31311849 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MFSCAKAYED11QNYSALKRAC21LRKKVLFEDP31LFPATDDSLY41YKGTPGPTVR
51-10051WKRPKDICDD61PRLFVDGISS71HDLHQGQVGN81CWFVAACSSL91ASRESLWQKV
101-150101IPDWKEQEWN111PEKPDSYAGI121FHFNFWRFGE131WVDVIVDDRL141PTVNNQLIYC
151-200151HSNSKNEFWC161ALVEKAYAKL171AGCYQALDGG181NTADALVDFT191GGVSEPIDLT
201-250201EGDLATDEAK211RNQLFERVLK221VHSRGGLISA231SIKAVTAADM241EARLACGLVK
251-300251GHAYAVTDVR261KVRLGHGLLA271FFKSEKLDMI281RLRNPWGERE291WTGPWSDTSE
301-350301EWQKVSKSER311EKMGVTVQDD321GEFWMTFEDM331CRYFTDIIKC341RLINTSYLSI
351-400351HKTWEEARLH361GAWTRHEDPQ371QNRSGGCINH381KDTFFQNPQY391VFEVKKPEDE
401-450401VLISIQQRPK411RSTRREGKGE421NLAIGFDIYK431VEENRQYRMH441SLQHKAASSI
451-500451YINSRSVFLR461TELPEGRYVI471IPTTFEPGHT481GEFLLRVFTD491VPSNCRELRL
501-550501DEPPRTCWSS511LCGYPQQVAQ521VHVLGAAGLK531DSPTGANSYV541IIKCEGEKVR
551-600551SAVQRGTSTP561EYNVKGIFYR571KKLAQPITVQ581VWNHRVLKDE591FLGQVHLKTA
601-640601PDDLQDLHTL611HLQDRSSRQP621SDLPGIVAVR631VLCSASLTAV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
4 - - -
GPS-Palm: 0.94
Deep-Palm: 0.02
20 Papain-like cysteine peptidase superfamily - -
GPS-Palm: 0.92
Deep-Palm: 0.96
58 - - -
Deep-Palm: 0.70
81 - - -
Deep-Palm: 0.19
87 - - -
Deep-Palm: 0.23
150 - - -
Deep-Palm: 0.14
160 - -
Brain (35358180)
Deep-Palm: 0.27
173 - -
Brain (35358180)
Deep-Palm: 0.94
246 - - -
Deep-Palm: 0.92
331 - - -
Deep-Palm: 0.02
340 - - -
Deep-Palm: 0.06
377 - - -
Deep-Palm: 0.06
495 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
Brain (35358180)
GPS-Palm: 0.91
Deep-Palm: 0.93
507 SWISSPALM DBPTM CYSMODDB -
Brain (31311849)
Forebrain (28680068)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.70
512 SWISSPALM DBPTM CYSMODDB -
Brain (31311849)
Forebrain (28680068)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.89
544 - - -
Deep-Palm: 0.65
633 - - -
GPS-Palm: 0.92
Deep-Palm: 0.13
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
Brain
Specificity: 0.158
3/3 (100.0%)
1
Liver
Specificity: 0.053
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
15
Brain tissue (Mass)
Specificity: 0.789
15/56 (26.8%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine