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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O08738 Casp6 Caspase-6 (CASP-6) (EC 3.4.22.59) (Apoptotic … Mus musculus (Mouse) 276 aa

Protein Details: O08738 (Casp6)

Protein Information
AccessionO08738
Protein NamesCaspase-6 (CASP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18; Caspase-6 subunit p11]
Gene SymbolCasp6
OrganismMus musculus (Mouse)
Length276 aa
IsoformsNo isoforms
Related PMIDs 35477839
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MTETDGFYKS11REVFDPAEQY21KMDHKRRGVA31LIFNHERFFW41HLTLPERRGT
51-10051NADRDNLTRR61FSDLGFEVKC71FNDLRAEELL81LKIHEVSTSS91HIDADCFICV
101-150101FLSHGEGNHV111YAYDAKIEIQ121TLTGLFKGDK131CQSLVGKPKI141FIIQACRGSQ
151-200151HDVPVVPLDM161VDHQTDKLDN171VTQVDAASVY181TLPAGADFLM191CYSVAEGYYS
201-250201HRETVNGSWY211IQDLCEMLAR221YGSSLEFTEL231LTLVNRKVSQ241RRVDFCKDPD
251-276251AIGKKQVPCF261ASMLTKKLHF271CPKPSK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
70 SWISSPALM DBPTM CYSMODDB Caspase domain
liver (26165157)
-
GPS-Palm: 0.69
Deep-Palm: 0.98
96 - - -
Deep-Palm: 0.03
99 - - -
Deep-Palm: 0.03
131 - - -
GPS-Palm: 0.73
Deep-Palm: 0.95
146 Caspase domain
MLE (39008777)
-
GPS-Palm: 0.90
Deep-Palm: 0.89
191 - - -
Deep-Palm: 0.88
215 - - -
Deep-Palm: 0.76
246 - - -
GPS-Palm: 0.81
Deep-Palm: 0.93
259 - - -
GPS-Palm: 0.88
Deep-Palm: 0.55
271 - - -
GPS-Palm: 0.95
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Testis
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine