Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O08749 | Dld | Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) … | Mus musculus (Mouse) | 509 aa |
Protein Details: O08749 (Dld)
Protein Information
| Accession | O08749 |
|---|---|
| Protein Names | Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) |
| Gene Symbol | Dld |
| Organism | Mus musculus (Mouse) |
| Length | 509 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29733200 31311849 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MQSWSRVYRS11LAKKGHFNRI21SHGLQGVSSV31PLRTYADQPI41EADVTVIGSG
51-10051PGGYVAAIKS61AQLGFKTVCI71EKNETLGGTC81LNVGCIPSKA91LLNNSHYYHM
101-150101AHGKDFASRG111IEIPEVRLNL121EKMMEQKHSA131VKALTGGIAH141LFKQNKVVHV
151-200151NGFGKITGKN161QVTATKADGS171TQVIDTKNIL181VATGSEVTPF191PGITIDEDTI
201-250201VSSTGALSLK211KVPEKLVVIG221AGVIGVELGS231VWQRLGADVT241AVEFLGHVGG
251-300251IGIDMEISKN261FQRILQRQGF271KFKLNTKVTG281ATKKSDGKID291VSVEAASGGK
301-350301AEVITCDVLL311VCIGRRPFTQ321NLGLEELGIE331LDPKGRIPVN341NRFQTKIPNI
351-400351YAIGDVVAGP361MLAHKAEDEG371IICVEGMAGG381AVHIDYNCVP391SVIYTHPEVA
401-450401WVGKSEEQLK411EEGIEFKIGK421FPFAANSRAK431TNADTDGMVK441ILGHKSTDRV
451-500451LGAHILGPGA461GEMVNEAALA471LEYGASCEDI481ARVCHAHPTL491SEAFREANLA
501-509501AAFGKPINF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 69 | Pyridine nucleotide-disulphide oxidoreductase |
Brain
(34200797)
| - |
GPS-Palm: 0.83
Deep-Palm: 0.97
|
|
| 80 | SWISSPALM DBPTM CYSMODDB | Pyridine nucleotide-disulphide oxidoreductase |
Liver
(28526873)
brain
(39008777)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.78
Deep-Palm: 0.93
|
| 85 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
brain
(39008777)
|
Brain
(35358180)
|
GPS-Palm: 0.91
Deep-Palm: 0.61
|
| 306 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.98
|
|
| 312 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.98
|
|
| 373 | - | - | - |
Deep-Palm: 0.52
|
|
| 388 | - | - | - |
Deep-Palm: 0.09
|
|
| 477 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.94
|
|
| 484 | SWISSPALM DBPTM CYSMODDB | Pyridine nucleotide-disulphide oxidoreductase dimerisation domain |
Brain
(31311849)
liver
(26165157)
Liver
(28526873)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.91
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.462
6
Liver
Specificity: 0.118
6/6 (100.0%)
5
Brain
Specificity: 0.098
5/5 (100.0%)
2
Testis
Specificity: 0.039
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
38
Brain tissue (Mass)
Specificity: 0.745
38/56 (67.9%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.