Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O08807 | Prdx4 | Peroxiredoxin-4 (EC 1.11.1.24) (Antioxidant enzyme … | Mus musculus (Mouse) | 274 aa |
Protein Details: O08807 (Prdx4)
Protein Information
| Accession | O08807 |
|---|---|
| Protein Names | Peroxiredoxin-4 (EC 1.11.1.24) (Antioxidant enzyme AOE372) (Peroxiredoxin IV) (Prx-IV) (Thioredoxin peroxidase AO372) (Thioredoxin-dependent peroxide reductase A0372) (Thioredoxin-dependent peroxiredoxin 4) |
| Gene Symbol | Prdx4 |
| Organism | Mus musculus (Mouse) |
| Length | 274 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEARSKLLDG11TTASRRWTRK21LVLLLPPLLL31FLLRTESLQG41LESDERFRTR
51-10051ENECHFYAGG61QVYPGEASRV71SVADHSLHLS81KAKISKPAPY91WEGTAVINGE
101-150101FKELKLTDYR111GKYLVFFFYP121LDFTFVCPTE131IIAFGDRIEE141FKSINTEVVA
151-200151CSVDSQFTHL161AWINTPRRQG171GLGPIRIPLL181SDLNHQISKD191YGVYLEDSGH
201-250201TLRGLFIIDD211KGVLRQITLN221DLPVGRSVDE231TLRLVQAFQY241TDKHGEVCPA
251-274251GWKPGSETII261PDPAGKLKYF271DKLN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 54 | - |
Brain
(34200797)
|
Brain
(35358180)
|
Deep-Palm: 0.74
|
|
| 127 | - | - | - |
Deep-Palm: 0.51
|
|
| 151 | SWISSPALM DBPTM CYSMODDB | AhpC/TSA family |
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.71
Deep-Palm: 0.35
|
| 248 | - | - |
Liver
(34884899)
Brain
(35358180)
|
Deep-Palm: 0.52
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
6
Liver
Specificity: 0.214
6/6 (100.0%)
2
Brain
Specificity: 0.071
2/2 (100.0%)
2
Testis
Specificity: 0.071
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
18
Brain tissue (Mass)
Specificity: 0.643
18/56 (32.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.