Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O08917 | Flot1 | Flotillin-1 | Mus musculus (Mouse) | 428 aa |
Protein Details: O08917 (Flot1)
Protein Information
| Accession | O08917 |
|---|---|
| Protein Names | Flotillin-1 |
| Gene Symbol | Flot1 |
| Organism | Mus musculus (Mouse) |
| Length | 428 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29660268 29733200 31311849 31772009 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MFFTCGPNEA11MVVSGFCRSP21PVMVAGGRVF31VLPCIQQIQR41ISLNTLTLNV
51-10051KSEKVYTRHG61VPISVTGIAQ71VKIQGQNKEM81LAAACQMFLG91KTEAEIAHIA
101-150101LETLEGHQRA111IMAHMTVEEI121YKDRQKFSEQ131VFKVASSDLV141NMGISVVSYT
151-200151LKDIHDDQDY161LHSLGKARTA171QVQKDARIGE181AEAKRDAGIR191EAKAKQEKVS
201-250201AQCLSEIEMA211KAQRDYELKK221ATYDIEVNTR231RAQADLAYQL241QVAKTKQQIE
251-300251EQRVQVQVVE261RAQQVAVQEQ271EIARREKELE281ARVRKPAEAE291RYRLERLAEA
301-350301EKAQLIMQAE311AEAESVRMRG321EAEAFAIGAR331ARAEAEQMAK341KAEAFQMYQE
351-400351AAQLDMLLEK361LPQVAEEISG371PLTSANKITL381VSSGSGTMGA391AKVTGEVLDI
401-428401LSRLPESVER411LTGVSISQVN421HNKPLRTA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 5 | SWISSPALM DBPTM CYSMODDB | - |
Forebrain
(28680068)
|
Brain
(35358180)
|
GPS-Palm: 0.86
Deep-Palm: 0.02
|
| 17 | SWISSPALM DBPTM CYSMODDB | - |
Forebrain
(28680068)
|
Brain
(35358180)
|
Deep-Palm: 0.83
|
| 34 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
Brain
(31311849)
Forebrain
(28680068)
brain
(39008777)
MLE
(39008777)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.95
Deep-Palm: 0.90
|
| 85 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
|
Liver
(34884899)
Brain
(35358180)
|
GPS-Palm: 0.73
Deep-Palm: 0.94
|
| 203 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
|
Liver
(34884899)
Brain
(35358180)
Macrophage Raw 264.7
(29217618)
|
GPS-Palm: 0.86
Deep-Palm: 0.95
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
6
Liver
Specificity: 0.111
6/6 (100.0%)
6
Brain
Specificity: 0.111
6/6 (100.0%)
2
Testis
Specificity: 0.037
2/2 (100.0%)
1
NSC
Specificity: 0.019
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.846
33
Brain tissue (Mass)
Specificity: 0.611
33/56 (58.9%)
4
Macrophage Raw 264.7 (Mass)
Specificity: 0.074
4/10 (40.0%)
2
Liver tissue (Mass)
Specificity: 0.037
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.