Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O09172 | Gclm | Glutamate--cysteine ligase regulatory subunit (GCS … | Mus musculus (Mouse) | 274 aa |
Protein Details: O09172 (Gclm)
Protein Information
| Accession | O09172 |
|---|---|
| Protein Names | Glutamate--cysteine ligase regulatory subunit (GCS light chain) (Gamma-ECS regulatory subunit) (Gamma-glutamylcysteine synthetase regulatory subunit) (Glutamate--cysteine ligase modifier subunit) |
| Gene Symbol | Gclm |
| Organism | Mus musculus (Mouse) |
| Length | 274 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 34884899 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGTDSRAAGA11LLARASTLHL21QTGNLLNWGR31LRKKCPSTHS41EELRDCIQKT
51-10051LNEWSSQISP61DLVREFPDVL71ECTMSHAVEK81INPDEREEMK91VSAKLFIVGS
101-150101NSSSSTRSAV111DMACSVLGVA121QLDSVIMASP131PIEDGVNLSL141EHLQPYWEEL
151-200151ENLVQSKKIV161AIGTSDLDKT171QLEQLYQWAQ181VKPNSNQVNL191ASCCVMPPDL
201-250201TAFAKQFDIQ211LLTHNDPKEL221LSEASFQEAL231QESIPDIEAQ241DWVPLWLLRY
251-274251SVIVKSRGII261KSKGYILQAK271RRGS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 35 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.85
|
| 46 | - | - | - |
Deep-Palm: 0.52
|
|
| 72 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.79
Deep-Palm: 0.85
|
| 114 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.91
|
|
| 193 | - | - | - |
Deep-Palm: 0.45
|
|
| 194 | - | - | - |
Deep-Palm: 0.81
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.714
5
Liver
Specificity: 0.500
5/5 (100.0%)
2
Testis
Specificity: 0.200
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Brain tissue (Mass)
Specificity: 0.300
3/56 (5.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.