Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O09173 | Hgd; Aku; Hgo | Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate … | Mus musculus (Mouse) | 445 aa |
Protein Details: O09173 (Hgd)
Protein Information
| Accession | O09173 |
|---|---|
| Protein Names | Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase) |
| Gene Symbol | Hgd; Aku; Hgo |
| Organism | Mus musculus (Mouse) |
| Length | 445 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 34884899 37925639 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.760
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
19
Liver tissue
Specificity: 0.760
19/19 (100.0%)
6
Liver membrane
Specificity: 0.240
6/6 (100.0%)
0
Brain tissue
Specificity: 0.000
0/12 (0.0%)
0
Macrophage Raw 264.7
Specificity: 0.000
0/2 (0.0%)
0
Neural Stem Cells
Specificity: 0.000
0/3 (0.0%)
0
Testis
Specificity: 0.000
0/2 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAELKYISGF11GNECASEDPR21CPGSLPKGQN31NPQVCPYNLY41AEQLSGSAFT
51-10051CPRNTNKRSW61LYRILPSVSH71KPFESIDQGH81VTHNWDEVGP91DPNQLRWKPF
101-150101EIPKASEKKV111DFVSGLYTLC121GAGDIKSNNG131LAVHIFLCNS141SMENRCFYNS
151-200151DGDFLIVPQK161GKLLIYTEFG171KMSLQPNEIC181VIQRGMRFSV191DVFEETRGYI
201-250201LEVYGVHFEL211PDLGPIGANG221LANPRDFLIP231VAWYEDRRVP241GGYTVINKFQ
251-300251GKLFACKQDV261SPFNVVAWHG271NYTPYKYNLE281NFMVINAVAF291DHADPSIFTV
301-350301LTAKSLRPGV311AIADFVIFPP321RWGVADKTFR331PPYYHRNCMS341EFMGLIKGHY
351-400351EAKQGGFLPG361GGSLHSAMTP371HGPDADCFEK381ASKAKLEPER391IADGTMAFMF
401-445401ESSLSLAVTK411WGLKTCSCLD421ENYYKCWEPL431RSHFTPNSRS441PTEPK
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 14 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Homogentisate 1 2-dioxygenase N-terminal | 28526873 |
| 35 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) | Homogentisate 1 2-dioxygenase N-terminal | 28526873 |
| 51 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | Homogentisate 1 2-dioxygenase N-terminal | 28526873 |
| 120 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Homogentisate 1 2-dioxygenase N-terminal | 28526873 |
| 180 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Homogentisate 1 2-dioxygenase N-terminal | 28526873 |
| 256 | Prediction (Low) | - | - |
| 338 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) | Homogentisate 1 2-dioxygenase C-terminal | 28526873 |
| 416 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | Homogentisate 1 2-dioxygenase C-terminal | 28526873 |
| 418 | Experimental Prediction (Low) | Homogentisate 1 2-dioxygenase C-terminal | 28526873 |