Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O14561 | NDUFAB1 | Acyl carrier protein, mitochondrial (ACP) … | Homo sapiens (Human) | 156 aa |
Protein Details: O14561 (NDUFAB1)
Protein Information
| Accession | O14561 |
|---|---|
| Protein Names | Acyl carrier protein, mitochondrial (ACP) (CI-SDAP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit) |
| Gene Symbol | NDUFAB1 |
| Organism | Homo sapiens (Human) |
| Length | 156 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 29733200 31251020 33636221 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MASRVLSAYV11SRLPAAFAPL21PRVRMLAVAR31PLSTALCSAG41TQTRLGTLQP
51-10051ALVLAQVPGR61VTQLCRQYSD71MPPLTLEGIQ81DRVLYVLKLY91DKIDPEKLSV
101-150101NSHFMKDLGL111DSLDQVEIIM121AMEDEFGFEI131PDIDAEKLMC141PQEIVDYIAD
151-156151KKDVYE
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 37 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.98
|
|
| 65 | - | - | - |
Deep-Palm: 0.97
|
|
| 140 | - | - |
LNCaP
(31251020)
cerebral cortex
(36430497)
|
Deep-Palm: 0.39
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.429
3
Jurkat T cell
Specificity: 0.300
3/3 (100.0%)
2
LNCaP
Specificity: 0.200
2/2 (100.0%)
1
HAP1 cell
Specificity: 0.100
1/1 (100.0%)
1
heart
Specificity: 0.100
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Cerebral Cortex (Mass)
Specificity: 0.200
2/4 (50.0%)
1
LNCaP cells (Mass)
Specificity: 0.100
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 65 | C → Y | 0.001014 | SNP | Missense Mutation | BRCA |
| 66 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |