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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O14595 CTDSP2; NIF2; OS4; SCP2 Carboxy-terminal domain RNA polymerase II … Homo sapiens (Human) 271 aa

Protein Details: O14595 (CTDSP2)

Protein Information
Accession O14595
Protein Names Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 2) (NLI-interacting factor 2) (Protein OS-4) (Small C-terminal domain phosphatase 2) (Small CTD phosphatase 2) (SCP2)
Gene Symbol CTDSP2; NIF2; OS4; SCP2
Organism Homo sapiens (Human)
Length 271 aa
Isoforms No isoforms
Related PMIDs 26111759 31251020
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.852
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
23
LNCaP cells
Specificity: 0.852
23/46 (50.0%)
4
T cells
Specificity: 0.148
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MEHGSIITQA11RREDALVLTK21QGLVSKSSPK31KPRGRNIFKA41LFCCFRAQHV
51-10051GQSSSSTELA61AYKEEANTIA71KSDLLQCLQY81QFYQIPGTCL91LPEVTEEDQG
101-150101RICVVIDLDE111TLVHSSFKPI121NNADFIVPIE131IEGTTHQVYV141LKRPYVDEFL
151-200151RRMGELFECV161LFTASLAKYA171DPVTDLLDRC181GVFRARLFRE191SCVFHQGCYV
201-250201KDLSRLGRDL211RKTLILDNSP221ASYIFHPENA231VPVQSWFDDM241ADTELLNLIP
251-271251IFEELSGAED261VYTSLGQLRA271P
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
43 Prediction (High) - -
44 Prediction (High) - -
77 Prediction (Low) - -
159 Prediction (High) - -
180 Prediction (Medium) - -
192 Prediction (Medium) - -
198 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
42 F → C 0.001887 SNP Missense Mutation UCEC
43 G → C 0.001014 SNP Missense Mutation BRCA
46 R → C 0.002141 SNP Missense Mutation SKCM
56 S → C 0.002033 SNP Missense Mutation LUSC
71 C → S 0.001014 SNP Missense Mutation BRCA
174 Y → C 0.001764 SNP Missense Mutation LUAD
225 C → W 0.002747 SNP Missense Mutation LIHC
225 C → C 0.001887 SNP Splice Region UCEC
236 W → C 0.002033 SNP Missense Mutation LUSC