Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O14595 | CTDSP2 | Carboxy-terminal domain RNA polymerase II … | Homo sapiens (Human) | 271 aa |
Protein Details: O14595 (CTDSP2)
Protein Information
| Accession | O14595 |
|---|---|
| Protein Names | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 2) (NLI-interacting factor 2) (Protein OS-4) (Small C-terminal domain phosphatase 2) (Small CTD phosphatase 2) (SCP2) |
| Gene Symbol | CTDSP2 |
| Organism | Homo sapiens (Human) |
| Length | 271 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 31251020 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEHGSIITQA11RREDALVLTK21QGLVSKSSPK31KPRGRNIFKA41LFCCFRAQHV
51-10051GQSSSSTELA61AYKEEANTIA71KSDLLQCLQY81QFYQIPGTCL91LPEVTEEDQG
101-150101RICVVIDLDE111TLVHSSFKPI121NNADFIVPIE131IEGTTHQVYV141LKRPYVDEFL
151-200151RRMGELFECV161LFTASLAKYA171DPVTDLLDRC181GVFRARLFRE191SCVFHQGCYV
201-250201KDLSRLGRDL211RKTLILDNSP221ASYIFHPENA231VPVQSWFDDM241ADTELLNLIP
251-271251IFEELSGAED261VYTSLGQLRA271P
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 43 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.95
|
|
| 44 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.95
|
|
| 77 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.73
|
|
| 89 | - | - | - |
Deep-Palm: 0.72
|
|
| 103 | - | - | - |
Deep-Palm: 0.89
|
|
| 159 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.78
|
|
| 180 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.95
|
|
| 192 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.90
|
|
| 198 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
Primary T cell
Specificity: 0.667
4/4 (100.0%)
2
LNCaP
Specificity: 0.333
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 42 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 46 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 56 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 236 | W → C | 0.002033 | SNP | Missense Mutation | LUSC |