Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O14880 | MGST3 | Glutathione S-transferase 3, mitochondrial (GST-3) … | Homo sapiens (Human) | 152 aa |
Protein Details: O14880 (MGST3)
Protein Information
| Accession | O14880 |
|---|---|
| Protein Names | Glutathione S-transferase 3, mitochondrial (GST-3) (EC 2.5.1.-) (Glutathione peroxidase MGST3) (EC 1.11.1.-) (LTC4 synthase MGST3) (EC 4.4.1.20) |
| Gene Symbol | MGST3 |
| Organism | Homo sapiens (Human) |
| Length | 152 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 29733200 31251020 32944167 33636221 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAVLSKEYGF11VLLTGAASFI21MVAHLAINVS31KARKKYKVEY41PIMYSTDPEN
51-10051GHIFNCIQRA61HQNTLEVYPP71FLFFLAVGGV81YHPRIASGLG91LAWIVGRVLY
101-150101AYGYYTGEPS111KRSRGALGSI121ALLGLVGTTV131CSAFQHLGWV141KSGLGSGPKC
151-152151CH
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 56 | - | - |
LNCaP
(31251020)
cerebral cortex
(36430497)
|
Deep-Palm: 0.12
|
|
| 131 | - |
HeLa
(37611173)
| - |
GPS-Palm: 0.76
Deep-Palm: 0.98
|
|
| 150 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.98
Deep-Palm: 0.01
|
| 151 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.98
Deep-Palm: 0.01
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.286
4
cerebral cortex
Specificity: 0.222
4/4 (100.0%)
2
LNCaP
Specificity: 0.111
2/2 (100.0%)
2
HAP1 cell
Specificity: 0.111
2/2 (100.0%)
2
PC3
Specificity: 0.111
2/2 (100.0%)
2
293T cell
Specificity: 0.111
2/2 (100.0%)
1
heart
Specificity: 0.056
1/1 (100.0%)
1
HUVECs
Specificity: 0.056
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.222
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 84 | R → C | 0.002545 | SNP | Missense Mutation | GBM |