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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O15127 SCAMP2 Secretory carrier-associated membrane protein 2 … Homo sapiens (Human) 329 aa

Protein Details: O15127 (SCAMP2)

Protein Information
Accession O15127
Protein Names Secretory carrier-associated membrane protein 2 (Secretory carrier membrane protein 2)
Gene Symbol SCAMP2
Organism Homo sapiens (Human)
Length 329 aa
Isoforms No isoforms
Related PMIDs 19137006 19801377 24357059 25914232 26111759 29575903 29733200 31251020 31382980 32651440 32944167 33636221 37611173
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.506
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
45
LNCaP cells
Specificity: 0.506
45/46 (97.8%)
13
Jurkat T cells
Specificity: 0.146
13/25 (52.0%)
10
HAP1 cells
Specificity: 0.112
10/10 (100.0%)
4
PC3 cells
Specificity: 0.045
4/4 (100.0%)
4
T cells
Specificity: 0.045
4/4 (100.0%)
4
293T cells
Specificity: 0.045
4/10 (40.0%)
3
CEMx174 cells
Specificity: 0.034
3/3 (100.0%)
2
DU145 cells
Specificity: 0.022
2/2 (100.0%)
1
U937 cells
Specificity: 0.011
1/1 (100.0%)
1
HeLa cells
Specificity: 0.011
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.011
1/2 (50.0%)
1
Liver membrane
Specificity: 0.011
1/1 (100.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSAFDTNPFA11DPVDVNPFQD21PSVTQLTNAP31QGGLAEFNPF41SETNAATTVP
51-10051VTQLPGSSQP61AVLQPSVEPT71QPTPQAVVSA81AQAGLLRQQE91ELDRKAAELE
101-150101RKERELQNTV111ANLHVRQNNW121PPLPSWCPVK131PCFYQDFSTE141IPADYQRICK
151-200151MLYYLWMLHS161VTLFLNLLAC171LAWFSGNSSK181GVDFGLSILW191FLIFTPCAFL
201-250201CWYRPIYKAF211RSDNSFSFFV221FFFVFFCQIG231IYIIQLVGIP241GLGDSGWIAA
251-300251LSTLDNHSLA261ISVIMMVVAG271FFTLCAVLSV281FLLQRVHSLY291RRTGASFQQA
301-329301QEEFSQGIFS311SRTFHRAASS321AAQGAFQGN
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
127 Experimental Prediction (Low) SCAMP family 37611173
132 Experimental Prediction (Medium) SCAMP family 37611173
197 CYSMODDB SWISSPALM DBPTM Prediction (Low) SCAMP family -
201 Prediction (Medium) - -
275 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
207 Y → C 0.002747 SNP Missense Mutation LIHC
215 S → C 0.002033 SNP Missense Mutation LUSC
227 C → Lfs*30 0.002288 INS Frame Shift Ins STAD
227 C → Vfs*3 0.003774 DEL Frame Shift Del UCEC
227 C → Lfs*30 0.001887 INS Frame Shift Ins UCEC