Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O15143 ARPC1B; ARC41 Actin-related protein 2/3 complex subunit … Homo sapiens (Human) 372 aa

Protein Details: O15143 (ARPC1B)

Protein Information
Accession O15143
Protein Names Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene Symbol ARPC1B; ARC41
Organism Homo sapiens (Human)
Length 372 aa
Isoforms No isoforms
Related PMIDs 29733200 31251020 31382980 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
12
LNCaP cells
Specificity: 0.600
12/46 (26.1%)
4
293T cells
Specificity: 0.200
4/10 (40.0%)
3
PC3 cells
Specificity: 0.150
3/4 (75.0%)
1
U937 cells
Specificity: 0.050
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAYHSFLVEP11ISCHAWNKDR21TQIAICPNNH31EVHIYEKSGA41KWTKVHELKE
51-10051HNGQVTGIDW61APESNRIVTC71GTDRNAYVWT81LKGRTWKPTL91VILRINRAAR
101-150101CVRWAPNENK111FAVGSGSRVI121SICYFEQEND131WWVCKHIKKP141IRSTVLSLDW
151-200151HPNNVLLAAG161SCDFKCRIFS171AYIKEVEERP181APTPWGSKMP191FGELMFESSS
201-250201SCGWVHGVCF211SASGSRVAWV221SHDSTVCLAD231ADKKMAVATL241ASETLPLLAL
251-300251TFITDNSLVA261AGHDCFPVLF271TYDAAAGMLS281FGGRLDVPKQ291SSQRGLTARE
301-350301RFQNLDKKAS311SEGGTAAGAG321LDSLHKNSVS331QISVLSGGKA341KCSQFCTTGM
351-372351DGGMSIWDVK361SLESALKDLK371IK
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
101 Prediction (High) - -
162 Prediction (Medium) - -
166 Prediction (Medium) - -
342 Prediction (Medium) - -
346 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
20 R → C 0.001887 SNP Missense Mutation UCEC
57 G → C 0.001887 SNP Missense Mutation UCEC
86 W → C 0.001887 SNP Missense Mutation UCEC
101 C → G 0.002288 SNP Missense Mutation STAD
101 C → C 0.002506 SNP Silent COAD
70* C → ? 0.001764 SNP Nonsense Mutation LUAD