Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O15551 | CLDN3; C7orf1; CPETR2 | Claudin-3 (Clostridium perfringens enterotoxin receptor … | Homo sapiens (Human) | 220 aa |
Protein Details: O15551 (CLDN3)
Protein Information
| Accession | O15551 |
|---|---|
| Protein Names | Claudin-3 (Clostridium perfringens enterotoxin receptor 2) (CPE-R 2) (CPE-receptor 2) (Rat ventral prostate.1 protein homolog) (hRVP1) |
| Gene Symbol | CLDN3; C7orf1; CPETR2 |
| Organism | Homo sapiens (Human) |
| Length | 220 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 29733200 31251020 32944167 |
| Database Sources | dbPTM PTMD SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.756
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
31
LNCaP cells
Specificity: 0.756
31/46 (67.4%)
4
PC3 cells
Specificity: 0.098
4/4 (100.0%)
4
HAP1 cells
Specificity: 0.098
4/10 (40.0%)
2
DU145 cells
Specificity: 0.049
2/2 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSMGLEITGT11ALAVLGWLGT21IVCCALPMWR31VSAFIGSNII41TSQNIWEGLW
51-10051MNCVVQSTGQ61MQCKVYDSLL71ALPQDLQAAR81ALIVVAILLA91AFGLLVALVG
101-150101AQCTNCVQDD111TAKAKITIVA121GVLFLLAALL131TLVPVSWSAN141TIIRDFYNPV
151-200151VPEAQKREMG161AGLYVGWAAA171ALQLLGGALL181CCSCPPREKK191YTATKVVYSA
201-220201PRSTGPGASL211GTGYDRKDYV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 23 | Prediction (Low) | - | - |
| 24 | Prediction (Medium) | - | - |
| 103 | DBPTM SWISSPALM Prediction (Medium) | - | - |
| 106 | DBPTM SWISSPALM Prediction (Low) | - | - |
| 181 | SWISSPALM PTMD Prediction (High) | - | - |
| 182 | DBPTM SWISSPALM PTMD Prediction (High) | - | - |
| 184 | DBPTM SWISSPALM PTMD Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 50 | W → C | 0.002033 | SNP | Missense Mutation | LUSC |