Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O35114 Scarb2 Lysosome membrane protein 2 (85 … Mus musculus (Mouse) 478 aa

Protein Details: O35114 (Scarb2)

Protein Information
AccessionO35114
Protein NamesLysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2)
Gene SymbolScarb2
OrganismMus musculus (Mouse)
Length478 aa
IsoformsNo isoforms
Related PMIDs 28526873 29733200 31772009 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGRCCFYTAG11TLSLLLLVTS21VTLLVARVFQ31KAVDQTIEKN41MVLQNGTKVF
51-10051NSWEKPPLPV61YIQFYFFNVT71NPEEILQGEI81PLLEEVGPYT91YRELRNKANI
101-150101QFGENGTTIS111AVTNKAYVFE121RNQSVGDPNV131DLIRTINIPL141LTVVDLAQLT
151-200151LLRELIEAML161KAYQQKLFVI171HTVHELLWGY181KDEILSLVHI191FKPDVSPNFG
201-250201LFYERNGTND211GEYVFLTGED221NYLNFSKIVE231WNGKTSLDWW241TTDTCNMING
251-300251TDGDSFHPLI261SKDEVLYLFP271SDLCRSVHIT281FSSFENVEGL291PAFRYKVPAE
301-350301ILANTSENAG311FCIPEGNCMD321SGVLNISICK331NGAPIIMSFP341HFYQADEKFV
351-400351SAIKGMHPNK361EEHESFVDIN371PLTGIILRGA381KRFQINTYVR391KLDDFVETGD
401-450401IRTMVFPVMY411LNESVLIDKE421TANQLKSVIN431TTLVVTNIPY441IIMALGVFFG
451-478451LVFTWLACRG461QGSMDEGTAD471ERAPLIRT
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
4 - - -
GPS-Palm: 0.93
Deep-Palm: 0.04
5 - - -
GPS-Palm: 0.95
Deep-Palm: 0.04
245 - - -
Deep-Palm: 0.03
274 SWISSPALM DBPTM CYSMODDB CD36 family
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.84
Deep-Palm: 0.85
312 - - -
Deep-Palm: 0.67
318 - - -
Deep-Palm: 0.19
329 - - -
GPS-Palm: 0.79
Deep-Palm: 0.10
458 - - -
GPS-Palm: 0.75
Deep-Palm: 0.91
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.545
6
Liver
Specificity: 0.158
6/6 (100.0%)
2
Brain
Specificity: 0.053
2/2 (100.0%)
2
Testis
Specificity: 0.053
2/2 (100.0%)
1
NSC
Specificity: 0.026
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
27
Brain tissue (Mass)
Specificity: 0.711
27/56 (48.2%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine