Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O35598 | Adam10 | Disintegrin and metalloproteinase domain-containing protein … | Mus musculus (Mouse) | 749 aa |
Protein Details: O35598 (Adam10)
Protein Information
| Accession | O35598 |
|---|---|
| Protein Names | Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) |
| Gene Symbol | Adam10 |
| Organism | Mus musculus (Mouse) |
| Length | 749 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29660268 35477839 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MVLPTVLILL11LSWAAGLGGQ21YGNPLNKYIR31HYEGLSYNVD41SLHQKHQRAK
51-10051RAVSHEDQFL61LLDFHAHGRQ71FNLRMKRDTS81LFSDEFKVET91SNKVLDYDTS
101-150101HIYTGHIYGE111EGSFSHGSVI121DGRFEGFIKT131RGGTFYIEPA141ERYIKDRILP
151-200151FHSVIYHEDD161INYPHKYGPQ171GGCADHSVFE181RMRKYQMTGV191EEGARAHPEK
201-250201HAASSGPELL211RKKRTTLAER221NTCQLYIQTD231HLFFKYYGTR241EAVIAQISSH
251-300251VKAIDTIYQT261TDFSGIRNIS271FMVKRIRINT281TSDEKDPTNP291FRFPNIGVEK
301-350301FLELNSEQNH311DDYCLAYVFT321DRDFDDGVLG331LAWVGAPSGS341SGGICEKSKL
351-400351YSDGKKKSLN361TGIITVQNYG371SHVPPKVSHI381TFAHEVGHNF391GSPHDSGTEC
401-450401TPGESKNLGQ411KENGNYIMYA421RATSGDKLNN431NKFSLCSIRN441ISQVLEKKRN
451-500451NCFVESGQPI461CGNGMVEQGE471ECDCGYSDQC481KDDCCFDANQ491PEGKKCKLKP
501-550501GKQCSPSQGP511CCTAQCAFKS521KSEKCRDDSD531CAKEGICNGF541TALCPASDPK
551-600551PNFTDCNRHT561QVCINGQCAG571SICEKYDLEE581CTCASSDGKD591DKELCHVCCM
601-650601KKMAPSTCAS611TGSLQWSKQF621SGRTITLQPG631SPCNDFRGYC641DVFMRCRLVD
651-700651ADGPLARLKK661AIFSPQLYEN671IAEWIVAHWW681AVLLMGIALI691MLMAGFIKIC
701-749701SVHTPSSNPK711LPPPKPLPGT721LKRRRPPQPI731QQPPRQRPRE741SYQMGHMRR
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 173 | - | - | - |
Deep-Palm: 0.06
|
|
| 223 | SWISSPALM DBPTM CYSMODDB | - |
liver
(26165157)
|
Brain
(35358180)
|
Deep-Palm: 0.90
|
| 314 | - | - | - |
Deep-Palm: 0.25
|
|
| 345 | Metallo-peptidase family M12B Reprolysin-like |
MLE
(39008777)
| - |
GPS-Palm: 0.73
Deep-Palm: 0.94
|
|
| 400 | - | - | - |
Deep-Palm: 0.07
|
|
| 436 | - |
MLE
(39008777)
|
Brain
(35358180)
|
GPS-Palm: 0.82
Deep-Palm: 0.89
|
|
| 452 | - | - | - |
Deep-Palm: 0.36
|
|
| 461 | - | - | - |
Deep-Palm: 0.04
|
|
| 472 | - | - | - |
Deep-Palm: 0.02
|
|
| 474 | - | - | - |
Deep-Palm: 0.02
|
|
| 480 | - | - | - |
Deep-Palm: 0.03
|
|
| 484 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.03
|
|
| 485 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.03
|
|
| 496 | - | - | - |
Deep-Palm: 0.06
|
|
| 504 | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.14
|
|
| 511 | - | - | - |
Deep-Palm: 0.22
|
|
| 512 | - | - | - |
Deep-Palm: 0.21
|
|
| 516 | - | - | - |
Deep-Palm: 0.06
|
|
| 525 | - | - | - |
Deep-Palm: 0.06
|
|
| 531 | - | - | - |
Deep-Palm: 0.17
|
|
| 537 | - | - | - |
Deep-Palm: 0.15
|
|
| 544 | - | - | - |
Deep-Palm: 0.18
|
|
| 556 | - | - | - |
Deep-Palm: 0.07
|
|
| 563 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.05
|
|
| 568 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.04
|
|
| 573 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.04
|
|
| 581 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.12
|
|
| 583 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.07
|
|
| 595 | - | - | - |
GPS-Palm: 0.65
Deep-Palm: 0.07
|
|
| 598 | - | - | - |
Deep-Palm: 0.16
|
|
| 599 | - | - | - |
Deep-Palm: 0.28
|
|
| 608 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.77
Deep-Palm: 0.15
|
|
| 633 | - |
brain
(39008777)
MLE
(39008777)
|
Brain
(35358180)
|
Deep-Palm: 0.30
|
|
| 640 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.79
Deep-Palm: 0.44
|
|
| 646 | - | - | - |
Deep-Palm: 0.88
|
|
| 700 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.67
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Testis
Specificity: 0.105
2/2 (100.0%)
1
Brain
Specificity: 0.053
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.875
14
Brain tissue (Mass)
Specificity: 0.737
14/56 (25.0%)
2
Liver tissue (Mass)
Specificity: 0.105
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.