Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O35598 Adam10; Kuz; Madm Disintegrin and metalloproteinase domain-containing protein … Mus musculus (Mouse) 749 aa

Protein Details: O35598 (Adam10)

Protein Information
Accession O35598
Protein Names Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)
Gene Symbol Adam10; Kuz; Madm
Organism Mus musculus (Mouse)
Length 749 aa
Isoforms No isoforms
Related PMIDs 26165157 29217618 29660268 31772009 35477839 39008777
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.429
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
3
Neural Stem Cells
Specificity: 0.429
3/3 (100.0%)
2
Testis
Specificity: 0.286
2/2 (100.0%)
1
Brain tissue
Specificity: 0.143
1/12 (8.3%)
1
Macrophage Raw 264.7
Specificity: 0.143
1/2 (50.0%)
0
Liver tissue
Specificity: 0.000
0/19 (0.0%)
0
Liver membrane
Specificity: 0.000
0/6 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MVLPTVLILL11LSWAAGLGGQ21YGNPLNKYIR31HYEGLSYNVD41SLHQKHQRAK
51-10051RAVSHEDQFL61LLDFHAHGRQ71FNLRMKRDTS81LFSDEFKVET91SNKVLDYDTS
101-150101HIYTGHIYGE111EGSFSHGSVI121DGRFEGFIKT131RGGTFYIEPA141ERYIKDRILP
151-200151FHSVIYHEDD161INYPHKYGPQ171GGCADHSVFE181RMRKYQMTGV191EEGARAHPEK
201-250201HAASSGPELL211RKKRTTLAER221NTCQLYIQTD231HLFFKYYGTR241EAVIAQISSH
251-300251VKAIDTIYQT261TDFSGIRNIS271FMVKRIRINT281TSDEKDPTNP291FRFPNIGVEK
301-350301FLELNSEQNH311DDYCLAYVFT321DRDFDDGVLG331LAWVGAPSGS341SGGICEKSKL
351-400351YSDGKKKSLN361TGIITVQNYG371SHVPPKVSHI381TFAHEVGHNF391GSPHDSGTEC
401-450401TPGESKNLGQ411KENGNYIMYA421RATSGDKLNN431NKFSLCSIRN441ISQVLEKKRN
451-500451NCFVESGQPI461CGNGMVEQGE471ECDCGYSDQC481KDDCCFDANQ491PEGKKCKLKP
501-550501GKQCSPSQGP511CCTAQCAFKS521KSEKCRDDSD531CAKEGICNGF541TALCPASDPK
551-600551PNFTDCNRHT561QVCINGQCAG571SICEKYDLEE581CTCASSDGKD591DKELCHVCCM
601-650601KKMAPSTCAS611TGSLQWSKQF621SGRTITLQPG631SPCNDFRGYC641DVFMRCRLVD
651-700651ADGPLARLKK661AIFSPQLYEN671IAEWIVAHWW681AVLLMGIALI691MLMAGFIKIC
701-749701SVHTPSSNPK711LPPPKPLPGT721LKRRRPPQPI731QQPPRQRPRE741SYQMGHMRR
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
223 Experimental CYSMODDB SWISSPALM DBPTM - 26165157, 39008777
345 Experimental Prediction (Low) Metallo-peptidase family M12B Reprolysin-like 39008777
436 Experimental Prediction (Medium) - 39008777
504 Prediction (Low) - -
595 Prediction (Low) - -
608 Prediction (Low) - -
633 Experimental ADAM10 cysteine-rich domain 39008777
640 Prediction (Medium) - -
700 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons