Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O43169 | CYB5B | Cytochrome b5 type B (Cytochrome … | Homo sapiens (Human) | 150 aa |
Protein Details: O43169 (CYB5B)
Protein Information
| Accession | O43169 |
|---|---|
| Protein Names | Cytochrome b5 type B (Cytochrome b5 outer mitochondrial membrane isoform) |
| Gene Symbol | CYB5B |
| Organism | Homo sapiens (Human) |
| Length | 150 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 24357059 25914232 29733200 31251020 32651440 33636221 36430497 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSGSMATAEA11SGSDGKGQEV21ETSVTYYRLE31EVAKRNSLKE41LWLVIHGRVY
51-10051DVTRFLNEHP61GGEEVLLEQA71GVDASESFED81VGHSSDAREM91LKQYYIGDIH
101-150101PSDLKPESGS111KDPSKNDTCK121SCWAYWILPI131IGAVLLGFLY141RYYTSESKSS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 119 | - | - | - |
Deep-Palm: 0.32
|
|
| 122 | - | - | - |
Deep-Palm: 0.82
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.214
3
CEM 174 cell
Specificity: 0.214
3/3 (100.0%)
2
LNCaP
Specificity: 0.143
2/2 (100.0%)
2
293T cell
Specificity: 0.143
2/2 (100.0%)
2
cerebral cortex
Specificity: 0.143
2/2 (100.0%)
1
HAP1 cell
Specificity: 0.071
1/1 (100.0%)
1
Jurkat T cell
Specificity: 0.071
1/1 (100.0%)
1
EC cell
Specificity: 0.071
1/1 (100.0%)
1
heart
Specificity: 0.071
1/1 (100.0%)
1
HUVECs
Specificity: 0.071
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 46 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |