Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O43286 | B4GALT5 | Beta-1,4-galactosyltransferase 5 (Beta-1,4-GalTase 5) (Beta4Gal-T5) … | Homo sapiens (Human) | 388 aa |
Protein Details: O43286 (B4GALT5)
Protein Information
| Accession | O43286 |
|---|---|
| Protein Names | Beta-1,4-galactosyltransferase 5 (Beta-1,4-GalTase 5) (Beta4Gal-T5) (b4Gal-T5) (EC 2.4.1.-) (Beta-1,4-GalT II) (Glucosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.274) (Lactosylceramide synthase) (LacCer synthase) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5) |
| Gene Symbol | B4GALT5 |
| Organism | Homo sapiens (Human) |
| Length | 388 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 32944167 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MRARRGLLRL11PRRSLLAALF21FFSLSSSLLY31FVYVAPGIVN41TYLFMMQAQG
51-10051ILIRDNVRTI61GAQVYEQVLR71SAYAKRNSSV81NDSDYPLDLN91HSETFLQTTT
101-150101FLPEDFTYFA111NHTCPERLPS121MKGPIDINMS131EIGMDYIHEL141FSKDPTIKLG
151-200151GHWKPSDCMP161RWKVAILIPF171RNRHEHLPVL181FRHLLPMLQR191QRLQFAFYVV
201-250201EQVGTQPFNR211AMLFNVGFQE221AMKDLDWDCL231IFHDVDHIPE241SDRNYYGCGQ
251-300251MPRHFATKLD261KYMYLLPYTE271FFGGVSGLTV281EQFRKINGFP291NAFWGWGGED
301-350301DDLWNRVQNA311GYSVSRPEGD321TGKYKSIPHH331HRGEVQFLGR341YALLRKSKER
351-388351QGLDGLNNLN361YFANITYDAL371YKNITVNLTP381ELAQVNEY
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 114 | - | - | - |
Deep-Palm: 0.15
|
|
| 158 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.43
|
|
| 229 | - | - | - |
Deep-Palm: 0.03
|
|
| 248 | - | - | - |
Deep-Palm: 0.07
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
PC3
Specificity: 0.500
1/1 (100.0%)
1
HUVECs
Specificity: 0.500
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 136 | Y → C | 0.005618 | SNP | Missense Mutation | PAAD |
| 158 | C → R | 0.002506 | SNP | Missense Mutation | COAD |
| 158 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 229 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |
| 255 | F → C | 0.002506 | SNP | Missense Mutation | COAD |