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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O43505 B4GAT1; B3GNT1; B3GNT6 Beta-1,4-glucuronyltransferase 1 (EC 2.4.1.-) (I-beta-1,3-N-acetylglucosaminyltransferase) … Homo sapiens (Human) 415 aa

Protein Details: O43505 (B4GAT1)

Protein Information
Accession O43505
Protein Names Beta-1,4-glucuronyltransferase 1 (EC 2.4.1.-) (I-beta-1,3-N-acetylglucosaminyltransferase) (iGnT) (N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase) (Poly-N-acetyllactosamine extension enzyme) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1)
Gene Symbol B4GAT1; B3GNT1; B3GNT6
Organism Homo sapiens (Human)
Length 415 aa
Isoforms No isoforms
Related PMIDs 19137006 26111759 29575903 29733200 31251020 32944167 33636221
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.732
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
41
LNCaP cells
Specificity: 0.732
41/46 (89.1%)
7
Jurkat T cells
Specificity: 0.125
7/25 (28.0%)
4
HAP1 cells
Specificity: 0.071
4/10 (40.0%)
3
PC3 cells
Specificity: 0.054
3/4 (75.0%)
1
Liver membrane
Specificity: 0.018
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MQMSYAIRCA11FYQLLLAALM21LVAMLQLLYL31SLLSGLHGQE41EQDQYFEFFP
51-10051PSPRSVDQVK61AQLRTALASG71GVLDASGDYR81VYRGLLKTTM91DPNDVILATH
101-150101ASVDNLLHLS111GLLERWEGPL121SVSVFAATKE131EAQLATVLAY141ALSSHCPDMR
151-200151ARVAMHLVCP161SRYEAAVPDP171REPGEFALLR181SCQEVFDKLA191RVAQPGINYA
201-250201LGTNVSYPNN211LLRNLAREGA221NYALVIDVDM231VPSEGLWRGL241REMLDQSNQW
251-300251GGTALVVPAF261EIRRARRMPM271NKNELVQLYQ281VGEVRPFYYG291LCTPCQAPTN
301-350301YSRWVNLPEE311SLLRPAYVVP321WQDPWEPFYV331AGGKVPTFDE341RFRQYGFNRI
351-400351SQACELHVAG361FDFEVLNEGF371LVHKGFKEAL381KFHPQKEAEN391QHNKILYRQF
401-415401KQELKAKYPN411SPRRC
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
9 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) - 29575903
146 Prediction (Medium) - -
159 Prediction (High) - -
182 Prediction (Low) - -
415 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
152 R → C 0.002747 SNP Missense Mutation LIHC
162 R → C 0.001887 SNP Missense Mutation UCEC
182 C → Y 0.001887 SNP Missense Mutation UCEC
183 G → C 0.001764 SNP Missense Mutation LUAD
258 R → C 0.002545 SNP Missense Mutation GBM
266 R → C 0.002506 SNP Missense Mutation COAD
266 R → C 0.001887 SNP Missense Mutation UCEC
288 Y → C 0.001887 SNP Missense Mutation UCEC