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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O43657 TSPAN6 Tetraspanin-6 (Tspan-6) (A15 homolog) (Putative … Homo sapiens (Human) 245 aa

Protein Details: O43657 (TSPAN6)

Protein Information
AccessionO43657
Protein NamesTetraspanin-6 (Tspan-6) (A15 homolog) (Putative NF-kappa-B-activating protein 321) (T245 protein) (Tetraspanin TM4-D) (Transmembrane 4 superfamily member 6)
Gene SymbolTSPAN6
OrganismHomo sapiens (Human)
Length245 aa
IsoformsNo isoforms
Related PMIDs 24357059 31251020 32944167
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MASPSRRLQT11KPVITCFKSV21LLIYTFIFWI31TGVILLAVGI41WGKVSLENYF
51-10051SLLNEKATNV61PFVLIATGTV71IILLGTFGCF81ATCRASAWML91KLYAMFLTLV
101-150101FLVELVAAIV111GFVFRHEIKN121SFKNNYEKAL131KQYNSTGDYR141SHAVDKIQNT
151-200151LHCCGVTDYR161DWTDTNYYSE171KGFPKSCCKL181EDCTPQRDAD191KVNNEGCFIK
201-245201VMTIIESEMG211VVAGISFGVA221CFQLIGIFLA231YCLSRAITNN241QYEIV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
16 - - -
GPS-Palm: 0.95
Deep-Palm: 0.70
79 - - -
GPS-Palm: 0.82
Deep-Palm: 0.97
83 - - -
GPS-Palm: 0.89
Deep-Palm: 0.95
153 - - -
Deep-Palm: 0.39
154 - - -
Deep-Palm: 0.47
177 SWISSPALM DBPTM CYSMODDB Tetraspanin family - -
GPS-Palm: 0.65
Deep-Palm: 0.42
178 SWISSPALM DBPTM CYSMODDB Tetraspanin family - -
GPS-Palm: 0.81
Deep-Palm: 0.57
183 SWISSPALM DBPTM CYSMODDB - - -
Deep-Palm: 0.35
197 - - -
GPS-Palm: 0.74
Deep-Palm: 0.30
221 - - -
GPS-Palm: 0.67
Deep-Palm: 0.70
232 - - -
GPS-Palm: 0.88
Deep-Palm: 0.45
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
PC3
Specificity: 0.500
3/3 (100.0%)
2
LNCaP
Specificity: 0.333
2/2 (100.0%)
1
HUVECs
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine