Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O55137 | Acot1 | Acyl-coenzyme A thioesterase 1 (Acyl-CoA … | Mus musculus (Mouse) | 419 aa |
Protein Details: O55137 (Acot1)
Protein Information
| Accession | O55137 |
|---|---|
| Protein Names | Acyl-coenzyme A thioesterase 1 (Acyl-CoA thioesterase 1) (EC 3.1.2.-) (CTE-I) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase) (Palmitoyl-coenzyme A thioesterase) (EC 3.1.2.2) |
| Gene Symbol | Acot1 |
| Organism | Mus musculus (Mouse) |
| Length | 419 aa |
| Isoforms | No isoforms |
| Related PMIDs | 34200797 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEATLNLEPS11GRSCWDEPLS21IAVRGLAPEQ31PVTLRSVLRD41EKGALFRAHA
51-10051RYRADSHGEL61DLARTPALGG71SFSGLEPMGL81LWAMEPDRPF91WRLVKRDVQT
101-150101PFVVELEVLD111GHEPDGGQRL121AHAVHERHFL131APGVRRVPVR141EGRVRATLFL
151-200151PPEPGPFPGI161IDLFGVGGGL171LEYRASLLAG181KGFAVMALAY191YNYDDLPKNM
201-250201ETMHMEYFEE211AVNYLRSHPE221VKGPGIGLLG231ISKGGELGLA241MASFLKGITA
251-300251AVVINGSVAA261VGNTISYKDE271TIPPVTILRN281QVKMTKDGLK291DVVDALQSPL
301-350301VDKKSFIPVE311RSDTTFLFLV321GQDDHNWKSE331FYADEISKRL341QAHGKEKPQI
351-400351ICYPAAGHYI361EPPYFPLCSA371GMHLLVGANI381TFGGEPKPHA391MAQLDAWQQL
401-419401QTFFHKQLGS411ECLHVSPKI
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 14 | Acyl-CoA thioester hydrolase/BAAT, N-terminal |
MLE
(39008777)
|
Brain
(35358180)
|
Deep-Palm: 0.93
|
|
| 352 | - | - | - |
Deep-Palm: 0.89
|
|
| 368 | - | - | - |
Deep-Palm: 0.79
|
|
| 412 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
Liver
Specificity: 0.300
3/3 (100.0%)
1
Brain
Specificity: 0.100
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Brain tissue (Mass)
Specificity: 0.600
6/56 (10.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.