Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O60443 | GSDME | Gasdermin-E (Inversely correlated with estrogen … | Homo sapiens (Human) | 496 aa |
Protein Details: O60443 (GSDME)
Protein Information
| Accession | O60443 |
|---|---|
| Protein Names | Gasdermin-E (Inversely correlated with estrogen receptor expression 1) (ICERE-1) (Non-syndromic hearing impairment protein 5) [Cleaved into: Gasdermin-E, N-terminal (GSDME-NT); Gasdermin-E, C-terminal (GSDME-CT)] |
| Gene Symbol | GSDME |
| Organism | Homo sapiens (Human) |
| Length | 496 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MFAKATRNFL11REVDADGDLI21AVSNLNDSDK31LQLLSLVTKK41KRFWCWQRPK
51-10051YQFLSLTLGD61VLIEDQFPSP71VVVESDFVKY81EGKFANHVSG91TLETALGKVK
101-150101LNLGGSSRVE111SQSSFGTLRK121QEVDLQQLIR131DSAERTINLR141NPVLQQVLEG
151-200151RNEVLCVLTQ161KITTMQKCVI171SEHMQVEEKC181GGIVGIQTKT191VQVSATEDGN
201-250201VTKDSNVVLE211IPAATTIAYG221VIELYVKLDG231QFEFCLLRGK241QGGFENKKRI
251-300251DSVYLDPLVF261REFAFIDMPD271AAHGISSQDG281PLSVLKQATL291LLERNFHPFA
301-350301ELPEPQQTAL311SDIFQAVLFD321DELLMVLEPV331CDDLVSGLSP341TVAVLGELKP
351-400351RQQQDLVAFL361QLVGCSLQGG371CPGPEDAGSK381QLFMTAYFLV391SALAEMPDSA
401-450401AALLGTCCKL411QIIPTLCHLL421RALSDDGVSD431LEDPTLTPLK441DTERFGIVQR
451-496451LFASADISLE461RLKSSVKAVI471LKDSKVFPLL481LCITLNGLCA491LGREHS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 45 | Gasdermin-E Gasdermin, pore forming domain | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.93
|
|
| 156 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.87
|
|
| 168 | - | - | - |
Deep-Palm: 0.26
|
|
| 180 | - | - | - |
Deep-Palm: 0.61
|
|
| 235 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.89
|
|
| 331 | - | - | - |
Deep-Palm: 0.97
|
|
| 365 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.95
|
|
| 371 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.94
|
|
| 407 | SWISSPALM | Gasdermin PUB domain | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.97
|
| 408 | SWISSPALM | Gasdermin PUB domain | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.96
|
| 417 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.96
|
|
| 482 | - | - | - |
Deep-Palm: 0.94
|
|
| 489 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.10
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)