Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O60503 | ADCY9; KIAA0520 | Adenylate cyclase type 9 (EC … | Homo sapiens (Human) | 1353 aa |
Protein Details: O60503 (ADCY9)
Protein Information
| Accession | O60503 |
|---|---|
| Protein Names | Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (ACIX) (Adenylyl cyclase 9) (AC9) |
| Gene Symbol | ADCY9; KIAA0520 |
| Organism | Homo sapiens (Human) |
| Length | 1353 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 33636221 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.895
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
34
LNCaP cells
Specificity: 0.895
34/46 (73.9%)
3
Cerebral cortex
Specificity: 0.079
3/4 (75.0%)
1
Liver membrane
Specificity: 0.026
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MASPPHQQLL11HHHSTEVSCD21SSGDSNSVRV31KINPKQLSSN41SHPKHCKYSI
51-10051SSSCSSSGDS61GGVPRRVGGG71GRLRRQKKLP81QLFERASSRW91WDPKFDSVNL
101-150101EEACLERCFP111QTQRRFRYAL121FYIGFACLLW131SIYFAVHMRS141RLIVMVAPAL
151-200151CFLLVCVGFF161LFTFTKLYAR171HYAWTSLALT181LLVFALTLAA191QFQVLTPVSG
201-250201RGDSSNLTAT211ARPTDTCLSQ221VGSFSMCIEV231LFLLYTVMHL241PLYLSLCLGV
251-300251AYSVLFETFG261YHFRDEACFP271SPGAGALHWE281LLSRGLLHGC291IHAIGVHLFV
301-350301MSQVRSRSTF311LKVGQSIMHG321KDLEVEKALK331ERMIHSVMPR341IIADDLMKQG
351-400351DEESENSVKR361HATSSPKNRK371KKSSIQKAPI381AFRPFKMQQI391EEVSILFADI
401-450401VGFTKMSANK411SAHALVGLLN421DLFGRFDRLC431EETKCEKIST441LGDCYYCVAG
451-500451CPEPRADHAY461CCIEMGLGMI471KAIEQFCQEK481KEMVNMRVGV491HTGTVLCGIL
501-550501GMRRFKFDVW511SNDVNLANLM521EQLGVAGKVH531ISEATAKYLD541DRYEMEDGKV
551-600551IERLGQSVVA561DQLKGLKTYL571ISGQRAKESR581CSCAEALLSG591FEVIDGSQVS
601-650601SGPRGQGTAS611SGNVSDLAQT621VKTFDNLKTC631PSCGITFAPK641SEAGAEGGAP
651-700651QNGCQDEHKN661STKASGGPNP671KTQNGLLSPP681QEEKLTNSQT691SLCEILQEKG
701-750701RWAGVSLDQS711ALLPLRFKNI721REKTDAHFVD731VIKEDSLMKD741YFFKPPINQF
751-800751SLNFLDQELE761RSYRTSYQEE771VIKNSPVKTF781ASPTFSSLLD791VFLSTTVFLT
801-850801LSTTCFLKYE811AATVPPPPAA821LAVFSAALLL831EVLSLAVSIR841MVFFLEDVMA
851-900851CTKRLLEWIA861GWLPRHCIGA871ILVSLPALAV881YSHVTSEYET891NIHFPVFTGS
901-950901AALIAVVHYC911NFCQLSSWMR921SSLATVVGAG931PLLLLYVSLC941PDSSVLTSPL
951-1000951DAVQNFSSER961NPCNSSVPRD971LRRPASLIGQ981EVVLVFFLLL991LLVWFLNREF
1001-10501001EVSYRLHYHG1011DVEADLHRTK1021IQSMRDQADW1031LLRNIIPYHV1041AEQLKVSQTY
1051-11001051SKNHDSGGVI1061FASIVNFSEF1071YEENYEGGKE1081CYRVLNELIG1091DFDELLSKPD
1101-11501101YSSIEKIKTI1111GATYMAASGL1121NTAQAQDGSH1131PQEHLQILFE1141FAKEMMRVVD
1151-12001151DFNNNMLWFN1161FKLRVGFNHG1171PLTAGVIGTT1181KLLYDIWGDT1191VNIASRMDTT
1201-12501201GVECRIQVSE1211ESYRVLSKMG1221YDFDYRGTVN1231VKGKGQMKTY1241LYPKCTDHRV
1251-13001251IPQHQLSISP1261DIRVQVDGSI1271GRSPTDEIAN1281LVPSVQYVDK1291TSLGSDSSTQ
1301-13501301AKDAHLSPKR1311PWKEPVKAEE1321RGRFGKAIEK1331DDCDETGIEE1341ANELTKLNVS
1351-13531351KSV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 104 | Prediction (Low) | - | - |
| 108 | Prediction (Medium) | - | - |
| 151 | Prediction (Low) | - | - |
| 430 | Prediction (Medium) | - | - |
| 462 | Prediction (Low) | - | - |
| 477 | Prediction (Low) | - | - |
| 497 | Prediction (High) | - | - |
| 581 | Prediction (Low) | - | - |
| 583 | Prediction (Low) | - | - |
| 630 | Prediction (High) | - | - |
| 633 | Prediction (Medium) | - | - |
| 693 | Prediction (Low) | - | - |
| 851 | Prediction (Medium) | - | - |
| 867 | Prediction (Low) | - | - |
| 910 | Prediction (Low) | - | - |
| 913 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 52 | S → C | 0.003460 | SNP | Missense Mutation | CESC |
| 104 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 122 | Y → C | 0.002976 | SNP | Missense Mutation | KIRC |
| 202 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 286 | L → Cfs*19 | 0.002506 | DEL | Frame Shift Del | COAD |
| 383 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 402 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 403 | F → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 428 | R → C | 0.003559 | SNP | Missense Mutation | KIRP |
| 435 | C → S | 0.002294 | SNP | Missense Mutation | OV |
| 450 | G → C | 0.002545 | SNP | Missense Mutation | GBM |
| 497 | C → C | 0.003559 | SNP | Silent | KIRP |
| 497 | C → C | 0.003460 | SNP | Silent | CESC |
| 580 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 583 | C → F | 0.002294 | SNP | Missense Mutation | OV |
| 633 | C → C | 0.004219 | SNP | Silent | SARC |
| 802 | S → C | 0.002545 | SNP | Missense Mutation | GBM |
| 944 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 969 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1000 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1051 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 1205 | R → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 1213 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |