Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O60508 CDC40; EHB3; PRP17; PRPF17 Pre-mRNA-processing factor 17 (Cell division … Homo sapiens (Human) 579 aa

Protein Details: O60508 (CDC40)

Protein Information
Accession O60508
Protein Names Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3) (PRP17 homolog) (hPRP17)
Gene Symbol CDC40; EHB3; PRP17; PRPF17
Organism Homo sapiens (Human)
Length 579 aa
Isoforms No isoforms
Related PMIDs 29733200 31251020
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.892
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
33
LNCaP cells
Specificity: 0.892
33/46 (71.7%)
4
HAP1 cells
Specificity: 0.108
4/10 (40.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSAAIAALAA11SYGSGSGSES21DSDSESSRCP31LPAADSLMHL41TKSPSSKPSL
51-10051AVAVDSAPEV61AVKEDLETGV71HLDPAVKEVQ81YNPTYETMFA91PEFGPENPFR
101-150101TQQMAAPRNM111LSGYAEPAHI121NDFMFEQQRR131TFATYGYALD141PSLDNHQVSA
151-200151KYIGSVEEAE161KNQGLTVFET171GQKKTEKRKK181FKENDASNID191GFLGPWAKYV
201-250201DEKDVAKPSE211EEQKELDEIT221AKRQKKGKQE231EEKPGEEKTI241LHVKEMYDYQ
251-300251GRSYLHIPQD261VGVNLRSTMP271PEKCYLPKKQ281IHVWSGHTKG291VSAVRLFPLS
301-350301GHLLLSCSMD311CKIKLWEVYG321ERRCLRTFIG331HSKAVRDICF341NTAGTQFLSA
351-400351AYDRYLKLWD361TETGQCISRF371TNRKVPYCVK381FNPDEDKQNL391FVAGMSDKKI
401-450401VQWDIRSGEI411VQEYDRHLGA421VNTIVFVDEN431RRFVSTSDDK441SLRVWEWDIP
451-500451VDFKYIAEPS461MHSMPAVTLS471PNGKWLACQS481MDNQILIFGA491QNRFRLNKKK
501-550501IFKGHMVAGY511ACQVDFSPDM521SYVISGDGNG531KLNIWDWKTT541KLYSRFKAHD
551-579551KVCIGAVWHP561HETSKVITCG571WDGLIKLWD
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
274 Prediction (Low) - -
307 CYSMODDB SWISSPALM DBPTM Prediction (Medium) WD domain G-beta repeat -
311 CYSMODDB SWISSPALM DBPTM WD domain G-beta repeat -
324 Prediction (Medium) - -
339 Prediction (Medium) - -
366 Prediction (High) - -
478 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
12 Y → C 0.002506 SNP Missense Mutation COAD
196 W → C 0.002288 SNP Missense Mutation STAD
247 Y → C 0.001764 SNP Missense Mutation LUAD
249 Y → C 0.001887 SNP Missense Mutation UCEC
323 R → C 0.001887 SNP Missense Mutation UCEC
433 F → C 0.001887 SNP Missense Mutation UCEC
435 S → delinsKDHNSGKC 0.002976 INS In Frame Ins KIRC
437 S → C 0.001764 SNP Missense Mutation LUAD
502 F → C 0.002506 SNP Missense Mutation COAD