Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O60810 | PRAMEF4 | PRAME family member 4 | Homo sapiens (Human) | 478 aa |
Protein Details: O60810 (PRAMEF4)
Protein Information
| Accession | O60810 |
|---|---|
| Protein Names | PRAME family member 4 |
| Gene Symbol | PRAMEF4 |
| Organism | Homo sapiens (Human) |
| Length | 478 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MKMSIWTPPR11LLELAGRSLL21RDQALAMSTL31EELPTELFPP41LFMEAFSRRR
51-10051CEALKLMVQS61WPFRRLPLRP71LIKMPCLEAF81QAVLDGLDAL91LNLGVRPRRW
101-150101KLQVLDLQDV111CENFWMVWSE121AMAHGCFLNA131KRNKKPVEDC141PRMKGRQPLT
151-200151VFVELWLKNR161TLDEYLTCLL171LWVKQRKDLL181HLCCKKLKIL191GMPFRNIRSI
201-250201LKMVNLDCIQ211EVEVNCKWVL221PILTQFTPYL231GHMRNLQKLI241LSHMDVSRYV
251-300251SPEQKKEIVT261QFTTQFLKLR271CLQKLYMNSV281SFLEGHLDQL291LSCLKTSLKF
301-350301LTITNCVLLE311SDLKHLSQCP321SISQLKTLDL331SGIRLTNYSL341VPLQILLEKV
351-400351AATLEYLDLD361DCGIIDSQVN371AILPALSRCF381ELNTFSFCGN391PICMATLENL
401-450401LSHTIILKNL411CVELYPAPRE421SYGADGTLCW431SRFAQIRAEL441MNRVRDLRHP
451-478451KRILFCTDYC461PDCGNRSFYD471LEADQYCC
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 51 | Prediction (Medium) | - | - |
| 76 | Prediction (Medium) | - | - |
| 126 | Prediction (Medium) | - | - |
| 140 | Prediction (High) | - | - |
| 168 | Prediction (High) | - | - |
| 183 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
| 184 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | - |
| 208 | Prediction (Medium) | - | - |
| 216 | Prediction (Low) | - | - |
| 271 | Prediction (Medium) | - | - |
| 293 | Prediction (Low) | - | - |
| 306 | Prediction (Medium) | - | - |
| 319 | Prediction (Low) | - | - |
| 411 | Prediction (Low) | - | - |
| 429 | Prediction (Low) | - | - |
| 456 | Prediction (Medium) | - | - |
| 460 | Prediction (Low) | - | - |
| 477 | Prediction (High) | - | - |
| 478 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 42 | F → C | 0.005435 | SNP | Missense Mutation | ESCA |
| 50 | R → C | 0.005618 | SNP | Missense Mutation | PAAD |
| 65 | R → C | 0.027027 | SNP | Missense Mutation | DLBC |
| 96 | R → C | 0.010707 | SNP | Missense Mutation | SKCM |
| 140 | C → S | 0.002747 | SNP | Missense Mutation | LIHC |
| 168 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| 216 | C → R | 0.002141 | SNP | Missense Mutation | SKCM |
| 248 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 306 | C → R | 0.002288 | SNP | Missense Mutation | STAD |
| 319 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |
| 338 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 377 | S → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 478 | C → S | 0.002545 | SNP | Missense Mutation | GBM |
| 429* | C → ? | 0.001969 | SNP | Nonsense Mutation | HNSC |