Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O75071 EFCAB14; KIAA0494 EF-hand calcium-binding domain-containing protein 14 Homo sapiens (Human) 495 aa

Protein Details: O75071 (EFCAB14)

Protein Information
Accession O75071
Protein Names EF-hand calcium-binding domain-containing protein 14
Gene Symbol EFCAB14; KIAA0494
Organism Homo sapiens (Human)
Length 495 aa
Isoforms No isoforms
Related PMIDs 19137006 19801377 26111759 31251020 31382980 33636221
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.711
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
27
LNCaP cells
Specificity: 0.711
27/46 (58.7%)
7
Jurkat T cells
Specificity: 0.184
7/25 (28.0%)
2
DU145 cells
Specificity: 0.053
2/2 (100.0%)
1
U937 cells
Specificity: 0.026
1/1 (100.0%)
1
Liver membrane
Specificity: 0.026
1/1 (100.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MKKRKELNAL11IGLAGDSRRK21KPKKGPSSHR31LLRTEPPDSD41SESSSEEEEE
51-10051FGVVGNRSRF61AKGDYLRCCK71ICYPLCGFVI81LAACVVACVG91LVWMQVALKE
101-150101DLDALKEKFR111TMESNQKSSF121QEIPKLNEEL131LSKQKQLEKI141ESGEMGLNKV
151-200151WINITEMNKQ161ISLLTSAVNH171LKANVKSAAD181LISLPTTVEG191LQKSVASIGN
201-250201TLNSVHLAVE211ALQKTVDEHK221KTMELLQSDM231NQHFLKETPG241SNQIIPSPSA
251-300251TSELDNKTHS261ENLKQDILYL271HNSLEEVNSA281LVGYQRQNDL291KLEGMNETVS
301-350301NLTQRVNLIE311SDVVAMSKVE321KKANLSFSMM331GDRSATLKRQ341SLDQVTNRTD
351-400351TVKIQSIKKE361DSSNSQVSKL371REKLQLISAL381TNKPESNRPP391ETADEEQVES
401-450401FTSKPSALPK411FSQFLGDPVE421KAAQLRPISL431PGVSSTEDLQ441DLFRKTGQDV
451-495451DGKLTYQEIW461TSLGSAMPEP471ESLRAFDSDG481DGRYSFLELR491VALGI
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
68 Prediction (Low) - -
69 Prediction (Medium) - -
72 Prediction (Medium) - -
76 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
33 R → C 0.002427 SNP Missense Mutation BLCA
68 C → C 0.002294 SNP Silent OV
434 S → C 0.001969 SNP Missense Mutation HNSC