Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O75071 | EFCAB14 | EF-hand calcium-binding domain-containing protein 14 | Homo sapiens (Human) | 495 aa |
Protein Details: O75071 (EFCAB14)
Protein Information
| Accession | O75071 |
|---|---|
| Protein Names | EF-hand calcium-binding domain-containing protein 14 |
| Gene Symbol | EFCAB14 |
| Organism | Homo sapiens (Human) |
| Length | 495 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 31251020 31382980 33636221 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MKKRKELNAL11IGLAGDSRRK21KPKKGPSSHR31LLRTEPPDSD41SESSSEEEEE
51-10051FGVVGNRSRF61AKGDYLRCCK71ICYPLCGFVI81LAACVVACVG91LVWMQVALKE
101-150101DLDALKEKFR111TMESNQKSSF121QEIPKLNEEL131LSKQKQLEKI141ESGEMGLNKV
151-200151WINITEMNKQ161ISLLTSAVNH171LKANVKSAAD181LISLPTTVEG191LQKSVASIGN
201-250201TLNSVHLAVE211ALQKTVDEHK221KTMELLQSDM231NQHFLKETPG241SNQIIPSPSA
251-300251TSELDNKTHS261ENLKQDILYL271HNSLEEVNSA281LVGYQRQNDL291KLEGMNETVS
301-350301NLTQRVNLIE311SDVVAMSKVE321KKANLSFSMM331GDRSATLKRQ341SLDQVTNRTD
351-400351TVKIQSIKKE361DSSNSQVSKL371REKLQLISAL381TNKPESNRPP391ETADEEQVES
401-450401FTSKPSALPK411FSQFLGDPVE421KAAQLRPISL431PGVSSTEDLQ441DLFRKTGQDV
451-495451DGKLTYQEIW461TSLGSAMPEP471ESLRAFDSDG481DGRYSFLELR491VALGI
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 68 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.85
|
|
| 69 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.79
|
|
| 72 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.71
|
|
| 76 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.42
|
|
| 84 | - | - | - |
Deep-Palm: 0.28
|
|
| 88 | - | - | - |
Deep-Palm: 0.76
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.429
3
LNCaP
Specificity: 0.429
3/3 (100.0%)
2
Jurkat T cell
Specificity: 0.286
2/2 (100.0%)
1
U937 cell
Specificity: 0.143
1/1 (100.0%)
1
heart
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 33 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 68 | C → C | 0.002294 | SNP | Silent | OV |
| 434 | S → C | 0.001969 | SNP | Missense Mutation | HNSC |