Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O75131 CPNE3; CPN3; KIAA0636 Copine-3 (Copine III) Homo sapiens (Human) 537 aa

Protein Details: O75131 (CPNE3)

Protein Information
Accession O75131
Protein Names Copine-3 (Copine III)
Gene Symbol CPNE3; CPN3; KIAA0636
Organism Homo sapiens (Human)
Length 537 aa
Isoforms No isoforms
Related PMIDs 29733200 31251020 32944167 33636221 36430497 37611173
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.611
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
33
LNCaP cells
Specificity: 0.611
33/46 (71.7%)
10
HAP1 cells
Specificity: 0.185
10/10 (100.0%)
4
293T cells
Specificity: 0.074
4/10 (40.0%)
3
PC3 cells
Specificity: 0.056
3/4 (75.0%)
3
Cerebral cortex
Specificity: 0.056
3/4 (75.0%)
1
Liver membrane
Specificity: 0.019
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAAQCVTKVA11LNVSCANLLD21KDIGSKSDPL31CVLFLNTSGQ41QWYEVERTER
51-10051IKNCLNPQFS61KTFIIDYYFE71VVQKLKFGVY81DIDNKTIELS91DDDFLGECEC
101-150101TLGQIVSSKK111LTRPLVMKTG121RPAGKGSITI131SAEEIKDNRV141VLFEMEARKL
151-200151DNKDLFGKSD161PYLEFHKQTS171DGNWLMVHRT181EVVKNNLNPV191WRPFKISLNS
201-250201LCYGDMDKTI211KVECYDYDND221GSHDLIGTFQ231TTMTKLKEAS241RSSPVEFECI
251-300251NEKKRQKKKS261YKNSGVISVK271QCEITVECTF281LDYIMGGCQL291NFTVGVDFTG
301-350301SNGDPRSPDS311LHYISPNGVN321EYLTALWSVG331LVIQDYDADK341MFPAFGFGAQ
351-400351IPPQWQVSHE361FPMNFNPSNP371YCNGIQGIVE381AYRSCLPQIK391LYGPTNFSPI
401-450401INHVARFAAA411ATQQQTASQY421FVLLIITDGV431ITDLDETRQA441IVNASRLPMS
451-500451IIIVGVGGAD461FSAMEFLDGD471GGSLRSPLGE481VAIRDIVQFV491PFRQFQNAPK
501-537501EALAQCVLAE511IPQQVVGYFN521TYKLLPPKNP531ATKQQKQ
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
5 Prediction (High) - -
15 Experimental Prediction (Medium) - 37611173
31 Experimental Prediction (Low) - 37611173
54 Prediction (Medium) - -
202 Prediction (Medium) - -
249 Prediction (Medium) - -
385 Prediction (High) - -
506 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
54 C → F 0.002033 SNP Missense Mutation LUSC
54 C → S 0.002033 SNP Missense Mutation LUSC
288 C → C 0.002506 SNP Silent COAD
336 Y → C 0.002033 SNP Missense Mutation LUSC
392 Y → C 0.001969 SNP Missense Mutation HNSC