Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O75508 | CLDN11 | Claudin-11 (Oligodendrocyte-specific protein) | Homo sapiens (Human) | 207 aa |
Protein Details: O75508 (CLDN11)
Protein Information
| Accession | O75508 |
|---|---|
| Protein Names | Claudin-11 (Oligodendrocyte-specific protein) |
| Gene Symbol | CLDN11 |
| Organism | Homo sapiens (Human) |
| Length | 207 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 26876311 32944167 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MVATCLQVVG11FVTSFVGWIG21VIVTTSTNDW31VVTCGYTIPT41CRKLDELGSK
51-10051GLWADCVMAT61GLYHCKPLVD71ILILPGYVQA81CRALMIAASV91LGLPAILLLL
101-150101TVLPCIRMGQ111EPGVAKYRRA121QLAGVLLILL131ALCALVATIW141FPVCAHRETT
151-200151IVSFGYSLYA161GWIGAVLCLV171GGCVILCCAG181DAQAFGENRF191YYTAGSSSPT
201-207201HAKSAHV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 5 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.02
|
|
| 34 | Claudin-11 | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.73
|
|
| 41 | Claudin, conserved site | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.72
|
|
| 56 | - | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.95
|
|
| 65 | - | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.59
|
|
| 81 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.80
Deep-Palm: 0.98
|
|
| 105 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.99
|
|
| 133 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.98
|
|
| 144 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.91
|
|
| 168 | - | - | - |
Deep-Palm: 0.78
|
|
| 173 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.92
|
|
| 177 | - | - | - |
Deep-Palm: 0.86
|
|
| 178 | - | - | - |
Deep-Palm: 0.94
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
PC3
Specificity: 0.286
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.286
4/4 (100.0%)
1
frontal cortex
Specificity: 0.071
1/1 (100.0%)
1
HUVECs
Specificity: 0.071
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.286
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 81 | C → C | 0.002288 | SNP | Silent | STAD |
| 81 | C → C | 0.002141 | SNP | Silent | SKCM |
| 133 | C → C | 0.001887 | SNP | Silent | UCEC |
| 168 | C → Y | 0.001969 | SNP | Missense Mutation | HNSC |
| 168 | C → C | 0.001887 | SNP | Silent | UCEC |
| 189 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| ? | ? → ? | 0.001887 | SNP | Missense Mutation | UCEC |