Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O75558 | STX11 | Syntaxin-11 | Homo sapiens (Human) | 287 aa |
Protein Details: O75558 (STX11)
Protein Information
| Accession | O75558 |
|---|---|
| Protein Names | Syntaxin-11 |
| Gene Symbol | STX11 |
| Organism | Homo sapiens (Human) |
| Length | 287 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 24357059 26111759 33636221 |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MKDRLAELLD11LSKQYDQQFP21DGDDEFDSPH31EDIVFETDHI41LESLYRDIRD
51-10051IQDENQLLVA61DVKRLGKQNA71RFLTSMRRLS81SIKRDTNSIA91KAIKARGEVI
101-150101HCKLRAMKEL111SEAAEAQHGP121HSAVARISRA131QYNALTLTFQ141RAMHDYNQAE
151-200151MKQRDNCKIR161IQRQLEIMGK171EVSGDQIEDM181FEQGKWDVFS191ENLLADVKGA
201-250201RAALNEIESR211HRELLRLESR221IRDVHELFLQ231MAVLVEKQAD241TLNVIELNVQ
251-287251KTVDYTGQAK261AQVRKAVQYE271EKNPCRTLCC281FCCPCLK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 102 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.97
|
|
| 157 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.20
|
|
| 275 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.31
|
|
| 279 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.02
|
| 280 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
| 282 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.98
Deep-Palm: 0.02
|
| 283 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.98
Deep-Palm: 0.02
|
| 285 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.98
Deep-Palm: 0.01
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
4
Primary T cell
Specificity: 0.444
4/4 (100.0%)
2
Jurkat T cell
Specificity: 0.222
2/2 (100.0%)
1
EC cell
Specificity: 0.111
1/1 (100.0%)
1
heart
Specificity: 0.111
1/1 (100.0%)
1
HUVECs
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 45 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 78 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 105 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 105 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 105 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 220 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 255 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |