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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O75558 STX11 Syntaxin-11 Homo sapiens (Human) 287 aa

Protein Details: O75558 (STX11)

Protein Information
Accession O75558
Protein Names Syntaxin-11
Gene Symbol STX11
Organism Homo sapiens (Human)
Length 287 aa
Isoforms No isoforms
Related PMIDs 22496122 24357059 26111759 33636221
Database Sources dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
4
T cells
Specificity: 0.444
4/4 (100.0%)
2
Jurkat T cells
Specificity: 0.222
2/25 (8.0%)
2
Endothelial cells
Specificity: 0.222
2/2 (100.0%)
1
Liver membrane
Specificity: 0.111
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MKDRLAELLD11LSKQYDQQFP21DGDDEFDSPH31EDIVFETDHI41LESLYRDIRD
51-10051IQDENQLLVA61DVKRLGKQNA71RFLTSMRRLS81SIKRDTNSIA91KAIKARGEVI
101-150101HCKLRAMKEL111SEAAEAQHGP121HSAVARISRA131QYNALTLTFQ141RAMHDYNQAE
151-200151MKQRDNCKIR161IQRQLEIMGK171EVSGDQIEDM181FEQGKWDVFS191ENLLADVKGA
201-250201RAALNEIESR211HRELLRLESR221IRDVHELFLQ231MAVLVEKQAD241TLNVIELNVQ
251-287251KTVDYTGQAK261AQVRKAVQYE271EKNPCRTLCC281FCCPCLK
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
102 Prediction (Medium) - -
157 Prediction (Low) - -
275 Prediction (Medium) - -
279 DBPTM SWISSPALM Prediction (High) - -
280 DBPTM SWISSPALM Prediction (High) - -
282 DBPTM SWISSPALM Prediction (High) - -
283 DBPTM SWISSPALM Prediction (High) - -
285 DBPTM SWISSPALM Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
45 Y → C 0.002288 SNP Missense Mutation STAD
78 R → C 0.002288 SNP Missense Mutation STAD
105 R → C 0.001014 SNP Missense Mutation BRCA
105 R → C 0.001887 SNP Missense Mutation UCEC
105 R → C 0.003460 SNP Missense Mutation CESC
220 R → C 0.002506 SNP Missense Mutation COAD
255 Y → C 0.002506 SNP Missense Mutation COAD