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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O75608-2 LYPLA1 Acyl-protein thioesterase 1 (APT-1) (hAPT1) … Homo sapiens (Human) 214 aa

Protein Details: O75608-2 (LYPLA1)

Protein Information
AccessionO75608-2
Protein NamesAcyl-protein thioesterase 1 (APT-1) (hAPT1) (EC 3.1.2.-) (Lysophospholipase 1) (Lysophospholipase I) (LPL-I) (LysoPLA I) (Palmitoyl-protein hydrolase) (EC 3.1.2.22)
Gene SymbolLYPLA1
OrganismHomo sapiens (Human)
Length214 aa
Isoforms
Related PMIDs 31251020
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MCGNNMSTPL11PAIVPAARKA21TAAVIFLHGL31GDTGHGWAEA41FAGIRSSHIK
51-10051YICPHAFDII61GLSPDSQEDE71SGIKQAAENI81KALIDQEVKN91GIPSNRIILG
101-150101GFSQGGALSL111YTALTTQQKL121AGVTALSCWL131PLRASFPQGP141IGGANRDISI
151-200151LQCHGDCDPL161VPLMFGSLTV171EKLKTLVNPA181NVTFKTYEGM191MHSSCQQEMM
201-214201DVKQFIDKLL211PPID
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
2 - - -
GPS-Palm: 0.95
Deep-Palm: 0.03
53 - - -
Deep-Palm: 0.61
128 Phospholipase/Carboxylesterase
HeLa (29575903)
-
GPS-Palm: 0.94
144 - - -
Deep-Palm: 0.97
169 - - -
Deep-Palm: 0.82
173 - - -
Deep-Palm: 0.79
211 - - -
Deep-Palm: 0.28
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine