Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O75716 | STK16 | Serine/threonine-protein kinase 16 (EC 2.7.11.1) … | Homo sapiens (Human) | 305 aa |
Protein Details: O75716 (STK16)
Protein Information
| Accession | O75716 |
|---|---|
| Protein Names | Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK) |
| Gene Symbol | STK16 |
| Organism | Homo sapiens (Human) |
| Length | 305 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 31251020 32944167 |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGHALCVCSR11GTVIIDNKRY21LFIQKLGEGG31FSYVDLVEGL41HDGHFYALKR
51-10051ILCHEQQDRE61EAQREADMHR71LFNHPNILRL81VAYCLRERGA91KHEAWLLLPF
101-150101FKRGTLWNEI111ERLKDKGNFL121TEDQILWLLL131GICRGLEAIH141AKGYAHRDLK
151-200151PTNILLGDEG161QPVLMDLGSM171NQACIHVEGS181RQALTLQDWA191AQRCTISYRA
201-250201PELFSVQSHC211VIDERTDVWS221LGCVLYAMMF231GEGPYDMVFQ241KGDSVALAVQ
251-300251NQLSIPQSPR261HSSALRQLLN271SMMTVDPHQR281PHIPLLLSQL291EALQPPAPGQ
301-305301HTTQI
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 6 | DBPTM | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.04
|
| 8 | DBPTM | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.03
|
| 53 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.58
|
|
| 84 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.89
|
|
| 133 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.77
|
|
| 174 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.62
|
|
| 194 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.92
|
|
| 210 | - | - | - |
Deep-Palm: 0.78
|
|
| 223 | - | - | - |
Deep-Palm: 0.08
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
4
Primary T cell
Specificity: 0.500
4/4 (100.0%)
3
LNCaP
Specificity: 0.375
3/3 (100.0%)
1
PC3
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 19 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 79 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 143 | G → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 194 | C → R | 0.002020 | SNP | Missense Mutation | PRAD |
| 223 | C → C | 0.001887 | SNP | Silent | UCEC |
| 280 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |