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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O75828 CBR3; SDR21C2 Carbonyl reductase [NADPH] 3 (EC … Homo sapiens (Human) 277 aa

Protein Details: O75828 (CBR3)

Protein Information
Accession O75828
Protein Names Carbonyl reductase [NADPH] 3 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase 3) (Quinone reductase CBR3) (EC 1.6.5.10) (Short chain dehydrogenase/reductase family 21C member 2)
Gene Symbol CBR3; SDR21C2
Organism Homo sapiens (Human)
Length 277 aa
Isoforms No isoforms
Related PMIDs 24357059 31251020 36430497
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.857
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
12
LNCaP cells
Specificity: 0.857
12/46 (26.1%)
1
Endothelial cells
Specificity: 0.071
1/2 (50.0%)
1
Cerebral cortex
Specificity: 0.071
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSSCSRVALV11TGANRGIGLA21IARELCRQFS31GDVVLTARDV41ARGQAAVQQL
51-10051QAEGLSPRFH61QLDIDDLQSI71RALRDFLRKE81YGGLNVLVNN91AAVAFKSDDP
101-150101MPFDIKAEMT111LKTNFFATRN121MCNELLPIMK131PHGRVVNISS141LQCLRAFENC
151-200151SEDLQERFHS161ETLTEGDLVD171LMKKFVEDTK181NEVHEREGWP191NSPYGVSKLG
201-250201VTVLSRILAR211RLDEKRKADR221ILVNACCPGP231VKTDMDGKDS241IRTVEEGAET
251-277251PVYLALLPPD261ATEPQGQLVH271DKVVQNW
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
4 Prediction (High) - -
26 Prediction (Medium) - -
122 Prediction (Low) - -
143 Prediction (Low) - -
226 Prediction (High) - -
227 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
158 F → C 0.001887 SNP Missense Mutation UCEC
226 C → G 0.002141 SNP Missense Mutation SKCM