Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O76031 | CLPX | ATP-dependent clpX-like chaperone, mitochondrial (EC … | Homo sapiens (Human) | 633 aa |
Protein Details: O76031 (CLPX)
Protein Information
| Accession | O76031 |
|---|---|
| Protein Names | ATP-dependent clpX-like chaperone, mitochondrial (EC 3.6.4.10) (ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial) (Caseinolytic mitochondrial matrix peptidase chaperone subunit X) |
| Gene Symbol | CLPX |
| Organism | Homo sapiens (Human) |
| Length | 633 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31251020 31382980 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.756
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
34
LNCaP cells
Specificity: 0.756
34/46 (73.9%)
10
HAP1 cells
Specificity: 0.222
10/10 (100.0%)
1
U937 cells
Specificity: 0.022
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPSCGACTCG11AAAVRLITSS21LASAQRGISG31GRIHMSVLGR41LGTFETQILQ
51-10051RAPLRSFTET61PAYFASKDGI71SKDGSGDGNK81KSASEGSSKK91SGSGNSGKGG
101-150101NQLRCPKCGD111LCTHVETFVS121STRFVKCEKC131HHFFVVLSEA141DSKKSIIKEP
151-200151ESAAEAVKLA161FQQKPPPPPK171KIYNYLDKYV181VGQSFAKKVL191SVAVYNHYKR
201-250201IYNNIPANLR211QQAEVEKQTS221LTPRELEIRR231REDEYRFTKL241LQIAGISPHG
251-300251NALGASMQQQ261VNQQIPQEKR271GGEVLDSSHD281DIKLEKSNIL291LLGPTGSGKT
301-350301LLAQTLAKCL311DVPFAICDCT321TLTQAGYVGE331DIESVIAKLL341QDANYNVEKA
351-400351QQGIVFLDEV361DKIGSVPGIH371QLRDVGGEGV381QQGLLKLLEG391TIVNVPEKNS
401-450401RKLRGETVQV411DTTNILFVAS421GAFNGLDRII431SRRKNEKYLG441FGTPSNLGKG
451-500451RRAAAAADLA461NRSGESNTHQ471DIEEKDRLLR481HVEARDLIEF491GMIPEFVGRL
501-550501PVVVPLHSLD511EKTLVQILTE521PRNAVIPQYQ531ALFSMDKCEL541NVTEDALKAI
551-600551ARLALERKTG561ARGLRSIMEK571LLLEPMFEVP581NSDIVCVEVD591KEVVEGKKEP
601-633601GYIRAPTKES611SEEEYDSGVE621EEGWPRQADA631ANS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 4 | Prediction (High) | - | - |
| 7 | Prediction (High) | - | - |
| 9 | Prediction (Medium) | - | - |
| 309 | Prediction (Low) | - | - |
| 317 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 93 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 198 | Y → C | 0.006993 | SNP | Missense Mutation | LAML |
| 202 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 626 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |