Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O88342 Wdr1 WD repeat-containing protein 1 (Actin-interacting … Mus musculus (Mouse) 606 aa

Protein Details: O88342 (Wdr1)

Protein Information
AccessionO88342
Protein NamesWD repeat-containing protein 1 (Actin-interacting protein 1) (AIP1)
Gene SymbolWdr1
OrganismMus musculus (Mouse)
Length606 aa
IsoformsNo isoforms
Related PMIDs 29733200 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPYEIKKVFA11SLPQVERGVS21KILGGDPKGD31HFLYTNGKCV41ILRNIDNPAI
51-10051ADIYTEHAHQ61VVVAKYAPSG71FYIASGDISG81KLRIWDTTQK91EHLLKYEYQP
101-150101FAGKIKDIAW111TEDSKRIAVV121GEGREKFGAV131FLWDTGSSVG141EITGHNKVIN
151-200151SVDIKQTRPY161RLATGSDDNC171AAFFEGPPFK181FKFTIGDHSR191FVNCVRFSPD
201-250201GNRFATASAD211GQIFIYDGKT221GEKVCALGES231KAHDGGIYAI241SWSPDSTHLL
251-300251SASGDKTSKI261WDVNVNSVVS271TFPMGSNVLD281QQLGCLWQKD291HLLSISLSGY
301-350301INYLDKNNPS311KPLRVIKGHS321KSIQCLTVHR331NGGKSYIYSG341SHDGHINYWD
351-400351SETGENDSFS361GKGHTNQVSR371MTVNESEQLV381SCSMDDTVRY391TNLTLRDYSG
401-450401QGVVKLDVQP411KCVAVGPGGY421TVVVCIGQIV431LLKDQKKCFS441IDNPGYEPEV
451-500451VAVHPGGDTV461AVGGTDGNVR471VYSILASTLK481DEGKLLEAKG491PVTDVAYSHD
501-550501GAFLAVCDAS511KVVTVFSVAD521GYSENNVFYG531HHAKIVCLAW541SPDNEHFASG
551-600551GMDMMVYVWT561LSDPETKVKI571QDAHRLHHVS581SLAWLDEHTL591VTTSHDASVK
601-606601EWTITY
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
39 WD40/YVTN repeat-like-containing domain superfamily WD-REPEATCONTAINING PROTEIN WDR1 - -
Deep-Palm: 0.63
170 -
Brain (34200797)
Brain (35358180)
Deep-Palm: 0.52
194 WD domain G-beta repeat
Brain (34200797)
-
GPS-Palm: 0.75
Deep-Palm: 0.50
225 WDR5 beta-propeller domain
MLE (39008777)
Brain (35358180)
GPS-Palm: 0.74
Deep-Palm: 0.81
285 - - -
Deep-Palm: 0.62
325 SWISSPALM DBPTM CYSMODDB WD domain, G-beta repeat
liver (26165157)
MLE (39008777)
Brain (35358180)
GPS-Palm: 0.89
Deep-Palm: 0.91
382 -
Brain (34200797)
Brain (35358180)
Deep-Palm: 0.34
412 - - -
Deep-Palm: 0.90
425 - - -
GPS-Palm: 0.78
Deep-Palm: 0.95
438 -
Brain (34200797)
-
Deep-Palm: 0.79
507 - -
Brain (35358180)
Deep-Palm: 0.88
537 - - -
Deep-Palm: 0.07
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
4
Brain
Specificity: 0.121
4/4 (100.0%)
4
Liver
Specificity: 0.121
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
25
Brain tissue (Mass)
Specificity: 0.758
25/56 (44.6%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine