Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O88531 | Ppt1 | Palmitoyl-protein thioesterase 1 (PPT-1) (EC … | Mus musculus (Mouse) | 306 aa |
Protein Details: O88531 (Ppt1)
Protein Information
| Accession | O88531 |
|---|---|
| Protein Names | Palmitoyl-protein thioesterase 1 (PPT-1) (EC 3.1.2.2) (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1) |
| Gene Symbol | Ppt1 |
| Organism | Mus musculus (Mouse) |
| Length | 306 aa |
| Isoforms | No isoforms |
| Related PMIDs | 34884899 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MASSCSRRLL11AAALLPWCCA21AWALGHLDPP31SPPPLVIWHG41MGDSCCNPMS
51-10051MGVIKKMVEK61EIPGIYVLSL71EIGKNMMEDV81ENSFFLNVNV91QVNMVCQILE
101-150101KDPKLQQGYN111AIGFSQGGQF121LRAVAQRCPT131PPMMTLISVG141GQHQGVFGLP
151-200151RCPGESSHIC161DFIRKSLNAG171AYSKLVQERL181VQAQYWHDPI191KESVYRNYSI
201-250201FLADINQERC211VNESYKKNLM221ALKKFVMVKF231FNDSIVDPVD241SEWFGFYRSG
251-300251QAKETIPLQE261STLYTEDRLG271LKKMDKAGKL281VFLAKEGDHL291QISKEWFTAH
301-306301IIPFLK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 5 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.04
|
|
| 18 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.96
|
|
| 19 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.97
|
|
| 45 | Alpha/Beta hydrolase fold Palmitoyl protein thioesterase | - | - |
Deep-Palm: 0.33
|
|
| 46 | Alpha/Beta hydrolase fold Palmitoyl protein thioesterase | - | - |
Deep-Palm: 0.41
|
|
| 96 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.48
|
|
| 128 | SWISSPALM DBPTM CYSMODDB | Palmitoyl protein thioesterase | - |
Brain
(35358180)
|
Deep-Palm: 0.87
|
| 152 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.76
|
|
| 160 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.78
Deep-Palm: 0.91
|
|
| 210 | - | - | - |
Deep-Palm: 0.47
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Liver
Specificity: 0.250
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
12
Brain tissue (Mass)
Specificity: 0.750
12/56 (21.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.