Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O88533 Ddc Aromatic-L-amino-acid decarboxylase (AADC) (EC 4.1.1.28) … Mus musculus (Mouse) 480 aa

Protein Details: O88533 (Ddc)

Protein Information
AccessionO88533
Protein NamesAromatic-L-amino-acid decarboxylase (AADC) (EC 4.1.1.28) (DOPA decarboxylase) (DDC)
Gene SymbolDdc
OrganismMus musculus (Mouse)
Length480 aa
IsoformsNo isoforms
Related PMIDs 29660268 37925639
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MDSREFRRRG11KEMVDYIADY21LDGIEGRPVY31PDVEPGYLRP41LIPATAPQEP
51-10051ETYEDIIKDI61EKIIMPGVTH71WHSPYFFAYF81PTASSYPAML91ADMLCGAIGC
101-150101IGFSWAASPA111CTELETVMMD121WLGKMLELPE131AFLAGRAGEG141GGVIQGSASE
151-200151ATLVALLAAR161TKVIRQLQAA171SPEFTQAAIM181EKLVAYTSDQ191AHSSVERAGL
201-250201IGGIKLKAVP211SDGNFSMRAS221ALREALERDK231AAGLIPFFVV241ATLGTTSCCS
251-300251FDNLLEVGPI261CNQEGVWLHI271DAAYAGSAFI281CPEFRYLLNG291VEFADSFNFN
301-350301PHKWLLVNFD311CSAMWVKRRT321DLTGAFNMDP331VYLKHSHQDS341GFITDYRHWQ
351-400351IPLGRRFRSL361KMWFVFRMYG371VKGLQAYIRK381HVELSHEFES391LVRQDPRFEI
401-450401CTEVILGLVC411FRLKGSNELN421ETLLQRINSA431KKIHLVPCRL441RDKFVLRFAV
451-480451CARTVESAHV461QLAWEHISDL471ASSVLRAEKE
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
95 - - -
Deep-Palm: 0.73
100 - - -
GPS-Palm: 0.69
Deep-Palm: 0.60
111 - - -
Deep-Palm: 0.43
248 - - -
GPS-Palm: 0.73
Deep-Palm: 0.62
249 - - -
GPS-Palm: 0.71
Deep-Palm: 0.56
261 - - -
Deep-Palm: 0.15
281 - - -
Deep-Palm: 0.56
311 - - -
GPS-Palm: 0.77
Deep-Palm: 0.42
401 - - -
Deep-Palm: 0.88
410 - - -
GPS-Palm: 0.89
Deep-Palm: 0.85
438 - - -
GPS-Palm: 0.89
Deep-Palm: 0.96
451 - - -
GPS-Palm: 0.84
Deep-Palm: 0.94
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
Liver
Specificity: 0.750
3/3 (100.0%)
1
Brain
Specificity: 0.250
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine