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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O88736 Hsd17b7 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 (17-beta-hydroxysteroid … Mus musculus (Mouse) 334 aa

Protein Details: O88736 (Hsd17b7)

Protein Information
AccessionO88736
Protein Names3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 (17-beta-hydroxysteroid dehydrogenase 7) (17-beta-HSD 7) (3-keto-steroid reductase) (EC 1.1.1.270) (Dihydrotestosterone oxidoreductase) (EC 1.1.1.210) (Estradiol 17-beta-dehydrogenase 7) (EC 1.1.1.62)
Gene SymbolHsd17b7
OrganismMus musculus (Mouse)
Length334 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MRKVVLITGA11SSGIGLALCG21RLLAEDDDLH31LCLACRNLSK41ARAVRDTLLA
51-10051SHPSAEVSIV61QMDVSSLQSV71VRGAEEVKQK81FQRLDYLYLN91AGILPNPQFN
101-150101LKAFFCGIFS111RNVIHMFTTA121EGILTQNDSV131TADGLQEVFE141TNLFGHFILI
151-200151RELEPLLCHA161DNPSQLIWTS171SRNAKKANFS181LEDIQHSKGP191EPYSSSKYAT
201-250201DLLNVALNRN211FNQKGLYSSV221MCPGVVMTNM231TYGILPPFIW241TLLLPIMWLL
251-300251RFFVNALTVT261PYNGAEALVW271LFHQKPESLN281PLTKYASATS291GFGTNYVTGQ
301-334301KMDIDEDTAE311KFYEVLLELE321KRVRTTVQKS331DHPS
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
19 3-Keto-Steroid Reductase/17-beta-Hydroxysteroid Dehydrogenase NAD(P)-binding domain superfamily Short-chain dehydrogenase/reductase SDR - -
GPS-Palm: 0.93
Deep-Palm: 0.98
32 NAD(P)-binding domain superfamily 3-Keto-Steroid Reductase/17-beta-Hydroxysteroid Dehydrogenase - -
GPS-Palm: 0.73
Deep-Palm: 0.83
35 3-Keto-Steroid Reductase/17-beta-Hydroxysteroid Dehydrogenase NAD(P)-binding domain superfamily - -
GPS-Palm: 0.83
Deep-Palm: 0.98
106 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
GPS-Palm: 0.88
Deep-Palm: 0.54
158 - - -
Deep-Palm: 0.94
222 - - -
Deep-Palm: 0.73
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Liver
Specificity: 1.000
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine