Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O88844 | Idh1 | Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) … | Mus musculus (Mouse) | 414 aa |
Protein Details: O88844 (Idh1)
Protein Information
| Accession | O88844 |
|---|---|
| Protein Names | Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (IDH1) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDPc) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) |
| Gene Symbol | Idh1 |
| Organism | Mus musculus (Mouse) |
| Length | 414 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29575903 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSRKIQGGSV11VEMQGDEMTR21IIWELIKEKL31ILPYVELDLH41SYDLGIENRD
51-10051ATNDQVTKDA61AEAIKKYNVG71VKCATITPDE81KRVEEFKLKQ91MWKSPNGTIR
101-150101NILGGTVFRE111AIICKNIPRL121VTGWVKPIII131GRHAYGDQYR141ATDFVVPGPG
151-200151KVEITYTPKD161GTQKVTYMVH171DFEEGGGVAM181GMYNQDKSIE191DFAHSSFQMA
201-250201LSKGWPLYLS211TKNTILKKYD221GRFKDIFQEI231YDKKYKSQFE241AQKICYEHRL
251-300251IDDMVAQAMK261SEGGFIWACK271NYDGDVQSDS281VAQGYGSLGM291MTSVLICPDG
301-350301KTVEAEAAHG311TVTRHYRMYQ321KGQETSTNPI331ASIFAWSRGL341AHRAKLDNNT
351-400351ELSFFAKALE361DVCIETIEAG371FMTKDLAACI381KGLPNVQRSD391YLNTFEFMDK
401-414401LGENLKAKLA411QAKL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 73 | SWISSPALM DBPTM CYSMODDB | - |
liver
(26165157)
MLE
(39008777)
| - |
GPS-Palm: 0.93
Deep-Palm: 0.97
|
| 114 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.87
|
|
| 245 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.29
|
| 269 | SWISSPALM DBPTM CYSMODDB | Isocitrate/isopropylmalate dehydrogenase |
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.84
Deep-Palm: 0.80
|
| 297 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.97
|
|
| 363 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.84
Deep-Palm: 0.93
|
| 379 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.91
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
6
Liver
Specificity: 0.222
6/6 (100.0%)
2
Raw 264.7
Specificity: 0.074
2/2 (100.0%)
1
Brain
Specificity: 0.037
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
18
Brain tissue (Mass)
Specificity: 0.667
18/56 (32.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.