Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O88908 Soat2 Sterol O-acyltransferase 2 (EC 2.3.1.26) … Mus musculus (Mouse) 525 aa

Protein Details: O88908 (Soat2)

Protein Information
AccessionO88908
Protein NamesSterol O-acyltransferase 2 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 2) (ACAT-2) (Cholesterol acyltransferase 2)
Gene SymbolSoat2
OrganismMus musculus (Mouse)
Length525 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MQPKVPQLRR11REGLGEEQEK21GARGGEGNAR31THGTPDLVQW41TRHMEAVKTQ
51-10051FLEQAQRELA61ELLDRALWEA71MQAYPKQDRP81LPSAAPDSTS91KTQELHPGKR
101-150101KVFITRKSLI111DELMEVQHFR121TIYHMFIAGL131CVLIISTLAI141DFIDEGRLML
151-200151EFDLLLFSFG161QLPLALMTWV171PMFLSTLLVP181YQTLWLWARP191RAGGAWMLGA
201-250201SLGCVLLAAH211AVVLCVLPVH221VSVRHELPPA231SRCVLVFEQV241RLLMKSYSFL
251-300251RETVPGIFCV261RGGKGISPPS271FSSYLYFLFC281PTLIYRETYP291RTPSIRWNYV
301-350301AKNFAQVLGC311LLYACFILGR321LCVPVFANMS331REPFSTRALL341LSILHATGPG
351-400351IFMLLLIFFA361FLHCWLNAFA371EMLRFGDRMF381YRDWWNSTSF391SNYYRTWNVV
401-450401VHDWLYSYVY411QDGLWLLGRR421ARGVAMLGVF431LVSAVVHEYI441FCFVLGFFYP
451-500451VMLMLFLVFG461GLLNFTMNDR471HTGPAWNILM481WTFLFMGQGI491QVSLYCQEWY
501-525501ARRHCPLPQT511TFWGMVTPRS521WSCHP
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
131 - - -
Deep-Palm: 0.17
204 - - -
Deep-Palm: 0.97
215 - - -
Deep-Palm: 0.95
233 - - -
GPS-Palm: 0.69
Deep-Palm: 0.88
259 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
GPS-Palm: 0.94
Deep-Palm: 0.92
280 - - -
Deep-Palm: 0.64
310 - - -
GPS-Palm: 0.83
Deep-Palm: 0.70
315 - - -
GPS-Palm: 0.81
Deep-Palm: 0.87
322 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
GPS-Palm: 0.92
Deep-Palm: 0.93
364 - - -
Deep-Palm: 0.27
442 - - -
Deep-Palm: 0.09
496 - - -
Deep-Palm: 0.22
505 - - -
Deep-Palm: 0.24
523 - - -
GPS-Palm: 0.96
Deep-Palm: 0.01
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Liver
Specificity: 1.000
6/6 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine