Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O88962 Cyp8b1; Cyp12 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (EC 1.14.14.139) (7-alpha-hydroxy-4-cholesten-3-one … Mus musculus (Mouse) 500 aa

Protein Details: O88962 (Cyp8b1)

Protein Information
Accession O88962
Protein Names 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (EC 1.14.14.139) (7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase) (CYPVIIIB1) (Cytochrome P450 8B1) (Sterol 12-alpha-hydroxylase)
Gene Symbol Cyp8b1; Cyp12
Organism Mus musculus (Mouse)
Length 500 aa
Isoforms No isoforms
Related PMIDs 28526873 37925639
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
19
Liver tissue
Specificity: 1.000
19/19 (100.0%)
0
Brain tissue
Specificity: 0.000
0/12 (0.0%)
0
Macrophage Raw 264.7
Specificity: 0.000
0/2 (0.0%)
0
Neural Stem Cells
Specificity: 0.000
0/3 (0.0%)
0
Testis
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/6 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MTLWCTVLGA11LLTVVGCLCL21SLLLRHRRPW31EPPLDKGFVP41WLGHSMAFRK
51-10051NMFEFLKGMR61AKHGDVFTVQ71LGGQYFTFVM81DPLSFGPIIK91NTEKALDFQS
101-150101YAKELVLKVF111GYQSVDGDHR121MIHLASTKHL131MGQGLEELNQ141AMLDSLSLVM
151-200151LGPKGSSLGA161SSWCEDGLFH171FCYRILFKAG181FLSLFGYTKD191KQQDLDEADE
201-250201LFRKFRRFDF211LFPRFVYSLL221GPREWVEVSQ231LQRLFHQRLS241VEQNLEKDGI
251-300251SCWLGYMLQF261LREQGIASSM271QDKFNFMMLW281ASQGNTGPTC291FWVLLFLLKH
301-350301QDAMKAVREE311ATRVMGKARL321EAKKSFTFTP331SALKHTPVLD341SVMEESLRLC
351-400351ATPTLLRVVQ361EDYVLKMASG371QEYQIRRGDK381VALFPYLSVH391MDPDIHPEPT
401-450401AFKYDRFLNP411DGTRKVDFYK421SGKKIHHYSM431PWGSGVSKCP441GRFFALSEMK
451-500451TFVLLMIMYF461DFKLVDPDIP471VPPIDPRRWG481FGTSQPSHEV491RFLYRLKPVQ
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
5 Prediction (Medium) - -
17 Prediction (High) - -
19 Prediction (High) - -
350 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) - 28526873
439 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons