Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O88962 | Cyp8b1 | 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (EC 1.14.14.139) (7-alpha-hydroxy-4-cholesten-3-one … | Mus musculus (Mouse) | 500 aa |
Protein Details: O88962 (Cyp8b1)
Protein Information
| Accession | O88962 |
|---|---|
| Protein Names | 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (EC 1.14.14.139) (7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase) (CYPVIIIB1) (Cytochrome P450 8B1) (Sterol 12-alpha-hydroxylase) |
| Gene Symbol | Cyp8b1 |
| Organism | Mus musculus (Mouse) |
| Length | 500 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 37925639 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTLWCTVLGA11LLTVVGCLCL21SLLLRHRRPW31EPPLDKGFVP41WLGHSMAFRK
51-10051NMFEFLKGMR61AKHGDVFTVQ71LGGQYFTFVM81DPLSFGPIIK91NTEKALDFQS
101-150101YAKELVLKVF111GYQSVDGDHR121MIHLASTKHL131MGQGLEELNQ141AMLDSLSLVM
151-200151LGPKGSSLGA161SSWCEDGLFH171FCYRILFKAG181FLSLFGYTKD191KQQDLDEADE
201-250201LFRKFRRFDF211LFPRFVYSLL221GPREWVEVSQ231LQRLFHQRLS241VEQNLEKDGI
251-300251SCWLGYMLQF261LREQGIASSM271QDKFNFMMLW281ASQGNTGPTC291FWVLLFLLKH
301-350301QDAMKAVREE311ATRVMGKARL321EAKKSFTFTP331SALKHTPVLD341SVMEESLRLC
351-400351ATPTLLRVVQ361EDYVLKMASG371QEYQIRRGDK381VALFPYLSVH391MDPDIHPEPT
401-450401AFKYDRFLNP411DGTRKVDFYK421SGKKIHHYSM431PWGSGVSKCP441GRFFALSEMK
451-500451TFVLLMIMYF461DFKLVDPDIP471VPPIDPRRWG481FGTSQPSHEV491RFLYRLKPVQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 5 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.03
|
|
| 17 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.98
|
|
| 19 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.98
|
|
| 164 | - | - | - |
Deep-Palm: 0.87
|
|
| 172 | - | - | - |
Deep-Palm: 0.88
|
|
| 252 | - | - | - |
Deep-Palm: 0.88
|
|
| 290 | - | - | - |
Deep-Palm: 0.62
|
|
| 350 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
| - |
GPS-Palm: 0.95
Deep-Palm: 0.98
|
| 439 | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.34
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Liver
Specificity: 1.000
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.