Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O88986 Gcat 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial … Mus musculus (Mouse) 416 aa

Protein Details: O88986 (Gcat)

Protein Information
AccessionO88986
Protein Names2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase)
Gene SymbolGcat
OrganismMus musculus (Mouse)
Length416 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MWASFMWHGA11LSPGRRAHSA21LAQLRCILDS31ELEGIRGAGT41WKSERVITSR
51-10051QGPSIRVDGI61SGGILNFCAN71NYLGLSSHPA81VIQAGLQTLE91EFGAGLSSTR
101-150101FICGTQSIHK111NLEAKIAHFH121QREDAILYPS131CFDANAGLFE141ALLTPEDAVL
151-200151SDELNHASII161DGIRLCKAHK171YRYRHLDMAD181LEAKLKEAQK191HRLRLVATDG
201-250201AFSMDGDIAP211LQDICRLAAQ221YGALVFVDEC231HATGFLGPTG241RGTDELLGVM
251-300251DQVTIINSTL261GKALGGASGG271YTTGPEPLVS281LLRQRSRPYL291FSNSLPPAVV
301-350301GCASKALDLL311MESNAIIQSM321AAKTRRFRSK331MEAAGFTVSG341ADHPICPVML
351-400351GDARLSSQMA361DDMLKKGIFV371IGFSYPVVPK381GKARIRVQIS391AVHSEEDIDR
401-416401CVEAFVEVGR411LHGALP
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
26 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
MLE (39008777)
-
Deep-Palm: 0.98
68 - - -
Deep-Palm: 0.96
103 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
GPS-Palm: 0.93
Deep-Palm: 0.96
131 - - -
Deep-Palm: 0.64
166 - - -
Deep-Palm: 0.52
215 SWISSPALM DBPTM CYSMODDB Aminotransferase class I and II
Liver (28526873)
-
Deep-Palm: 0.92
230 - - -
Deep-Palm: 0.95
302 - - -
Deep-Palm: 0.96
346 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (35358180)
Deep-Palm: 0.94
401 - - -
Deep-Palm: 0.94
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
6
Liver
Specificity: 0.429
6/6 (100.0%)
2
Testis
Specificity: 0.143
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Brain tissue (Mass)
Specificity: 0.429
6/56 (10.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine