Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O88990 Actn3 Alpha-actinin-3 (Alpha-actinin skeletal muscle isoform … Mus musculus (Mouse) 900 aa

Protein Details: O88990 (Actn3)

Protein Information
AccessionO88990
Protein NamesAlpha-actinin-3 (Alpha-actinin skeletal muscle isoform 3) (F-actin cross-linking protein)
Gene SymbolActn3
OrganismMus musculus (Mouse)
Length900 aa
IsoformsNo isoforms
Related PMIDs 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MMMVMQPEGL11GAGEGPFSGG21GGGEYMEQEE31DWDRDLLLDP41AWEKQQRKTF
51-10051TAWCNSHLRK61AGTQIENIEE71DFRNGLKLML81LLEVISGERL91PRPDKGKMRF
101-150101HKIANVNKAL111DFIASKGVKL121VSIGAEEIVD131GNLKMTLGMI141WTIILRFAIQ
151-200151DISVEETSAK161EGLLLWCQRK171TAPYRNVNVQ181NFHTSWKDGL191ALCALIHRHR
201-250201PDLIDYAKLR211KDDPIGNLNT221AFEVAEKYLD231IPKMLDAEDI241VNTPKPDEKA
251-300251IMTYVSCFYH261AFAGAEQAET271AANRICKVLA281VNQENEKLME291EYEKLASELL
301-350301EWIRRTVPWL311ENRVGEPSMS321AMQRKLEDFR331DYRRLHKPPR341VQEKCQLEIN
351-400351FNTLQTKLRL361SHRPAFMPSE371GKLVSDIANA381WRGLEQVEKG391YEDWLLSEIR
401-450401RLQRLQHLAE411KFQQKASLHE421AWTRGKEEML431NQHDYESASL441QEVRALLRRH
451-500451EAFESDLAAH461QDRVEHIAAL471AQELNELDYH481EAASVNSRCQ491AICDQWDNLG
501-550501TLTQKRRDAL511ERMEKLLETI521DQLQLEFARR531AAPFNNWLDG541AIEDLQDVWL
551-600551VHSVEETQSL561LTAHEQFKAT571LPEADRERGA581ILGIQGEIQK591ICQTYGLRPK
601-650601SGNPYITLSS611QDINNKWDTV621RKLVPSRDQT631LQEELARQQV641NERLRRQFAA
651-700651QANAIGPWIQ661GKVEEVGRLA671AGLAGSLEEQ681MAGLRQQEQN691IINYKSNIDR
701-750701LEGDHQLLQE711SLVFDNKHTV721YSMEHIRVGW731EQLLTSIART741INEVENQVLT
751-800751RDAKGLSQEQ761LNEFRASFNH771FDRKRNGMME781PDDFRACLIS791MGYDLGEVEF
801-850801ARIMTMVDPN811AAGVVTFQAF821IDFMTRETAE831TDTAEQVVAS841FKILAGDKNY
851-900851ITPEELRREL861PAEQAEYCIR871RMAPYKGSGA881PSGALDYVAF891SSALYGESDL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
54 - -
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.73
167 - -
Brain (35358180)
GPS-Palm: 0.96
Deep-Palm: 0.96
193 - - -
Deep-Palm: 0.92
257 - - -
Deep-Palm: 0.73
276 - - -
Deep-Palm: 0.95
345 -
MLE (39008777)
-
Deep-Palm: 0.88
489 - - -
Deep-Palm: 0.23
493 - - -
Deep-Palm: 0.36
592 - - -
GPS-Palm: 0.93
Deep-Palm: 0.92
787 - - -
Deep-Palm: 0.40
868 - - -
Deep-Palm: 0.98
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Liver tissue (Mass)
Specificity: 1.000
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine