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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O89013 Leprot Leptin receptor gene-related protein (Endospanin-1) … Mus musculus (Mouse) 131 aa

Protein Details: O89013 (Leprot)

Protein Information
AccessionO89013
Protein NamesLeptin receptor gene-related protein (Endospanin-1) (OB-R gene-related protein) (OB-RGRP)
Gene SymbolLeprot
OrganismMus musculus (Mouse)
Length131 aa
IsoformsNo isoforms
Related PMIDs 28526873 31311849 34200797 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAGVKALVAL11SFSGAIGLTF21LMLGCALEDY31GVYWPLFVLI41FYVISPIPYF
51-10051IAKRVTYDSD61ATSSACRELA71YFFTTGIVVS81AFGLPVVLAR91VDVIKWGACG
101-131101LVLAGNAVIF111LTIQGFFLVF121GRGDDFSWEQ131W
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
25 Vps55/LEPROT Prokaryotic membrane lipoprotein lipid attachment site profile. - -
Deep-Palm: 0.83
66 SWISSPALM DBPTM CYSMODDB Vacuolar protein sorting 55
Brain (31311849)
Forebrain (28680068)
Liver (28526873)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.94
99 - - -
Deep-Palm: 0.94
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
4
Liver
Specificity: 0.250
4/4 (100.0%)
3
Brain
Specificity: 0.188
3/3 (100.0%)
2
Testis
Specificity: 0.125
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
7
Brain tissue (Mass)
Specificity: 0.438
7/56 (12.5%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine